{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T21:32:01Z","timestamp":1771018321039,"version":"3.50.1"},"reference-count":12,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ORL"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Aims:&lt;\/i&gt;&lt;\/b&gt; To explore the clinical characteristics and treatment of malignant minor salivary gland carcinomas of the larynx.&lt;b&gt;&lt;i&gt; Methods:&lt;\/i&gt;&lt;\/b&gt; Clinical patient information regarding presentation, pathology, treatment and outcome was obtained through a review of patient charts. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Malignant minor salivary carcinomas in the larynx were confirmed pathologically in 15 patients (11 males, 4 females) between 2003 and 2010 in our hospital; 6 patients had mucoepidermoid carcinoma (MEC; 40%), 6 had adenoid cystic carcinoma (ACC; 40%) and 3 had adenocarcinoma (20%). The most common tumour location was the subglottis (60%), followed by the supraglottis (33%). In total, 13 patients underwent surgery, of which 10 (77%) had positive\/insufficient resection margins. The mean follow-up time was 42.3 months, with a range of 8-129 months. The 3- and 5-year overall survival rates were 46.7 and 20%, respectively. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Malignant minor salivary gland carcinoma of the larynx is a rare disease that showed male predominance in our study. The carcinomas were most often localised in the subglottic region, and the most common histological types were ACC and MEC. Wide-margin surgery with postoperative radiotherapy is advocated. The overall prognosis is poor compared to squamous cell carcinomas of the same location and tumour stage.<\/jats:p>","DOI":"10.1159\/000368322","type":"journal-article","created":{"date-parts":[[2014,11,13]],"date-time":"2014-11-13T12:51:12Z","timestamp":1415883072000},"page":"222-226","source":"Crossref","is-referenced-by-count":14,"title":["Malignant Minor Salivary Gland Carcinomas of the Larynx"],"prefix":"10.1159","volume":"76","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2909-8446","authenticated-orcid":false,"given":"Ming","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ke-nan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cai","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia-xing","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shu-yi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2014,11,13]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.132.7.767"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2005.11.005"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e318231e37f"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20802"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1258\/0022215021910078"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2012.02.003"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(85)90166-7"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2012-0349"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/28.5.339"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21083"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.4137\/CPath.S8435"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2010.02.001"}],"container-title":["ORL"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/368322","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/368322","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:48:21Z","timestamp":1745430501000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000368322"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":12,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2014,11,1]]},"published-print":{"date-parts":[[2014,12,2]]}},"URL":"https:\/\/doi.org\/10.1159\/000368322","archive":["Portico"],"relation":{},"ISSN":["0301-1569","1423-0275"],"issn-type":[{"value":"0301-1569","type":"print"},{"value":"1423-0275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}