{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T18:27:22Z","timestamp":1793298442725,"version":"4.5.0"},"reference-count":25,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2014,11,22]],"date-time":"2014-11-22T00:00:00Z","timestamp":1416614400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},{"start":{"date-parts":[[2014,11,22]],"date-time":"2014-11-22T00:00:00Z","timestamp":1416614400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Princ Pract"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objective:&lt;\/i&gt;&lt;\/b&gt; To assess exercise heart rate recovery (HRR) indices in patients with systemic sclerosis (SSc) for an assessment of their cardiac autonomic function. &lt;b&gt;&lt;i&gt;Subjects and Methods:&lt;\/i&gt;&lt;\/b&gt; Thirty-five patients with diffuse or limited SSc and 35 healthy controls were enrolled. All subjects underwent exercise testing and transthoracic echocardiography. The HRR indices were calculated by subtracting the first- (HRR1), second- (HRR2) and third-minute (HRR3) heart rates from the maximal heart rate. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The SSc and control groups were similar in age (45.2 \u00b1 11.6 vs. 43.9 \u00b1 10.0 years), had identical gender ratios (31 female\/4 male in both groups) and similar left ventricular ejection fraction (66.5 \u00b1 5.1 vs. 67.7 \u00b1 5.9%). The mean HRR1 (21.8 \u00b1 4.4 vs. 27.7 \u00b1 4.3 bpm, p = 0.001), HRR2 (43.8 \u00b1 6.3 vs. 47.6 \u00b1 4.4 bpm, p = 0.004) and HRR3 (58.8 \u00b1 10.3 vs. 63.6 \u00b1 7.3 bpm, p = 0.031) values were significantly lower in the SSc group than in the healthy controls. HRR indices were similar in the limited and diffuse SSc subgroups. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; The patients with SSc had lower HRR indices than normal subjects. Cardiac autonomic functions might be involved in SSc, even in patients without cardiac symptoms.<\/jats:p>","DOI":"10.1159\/000368359","type":"journal-article","created":{"date-parts":[[2014,11,24]],"date-time":"2014-11-24T07:40:58Z","timestamp":1416814858000},"page":"17-22","source":"Crossref","is-referenced-by-count":11,"title":["Assessment of Cardiac Autonomic Nervous System Involvement in Systemic Sclerosis via Exercise Heart Rate Recovery"],"prefix":"10.1159","volume":"24","author":[{"given":"Ugur 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