{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T08:45:47Z","timestamp":1782809147464,"version":"3.54.5"},"reference-count":14,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Background: Persistent erythema and severe rosacea flushing can cause significant physical discomfort and emotional stress to patients. Currently, no satisfactory treatments are available. Methods: We report two cases of refractory flushing and erythema of rosacea that were successfully treated with intradermal botulinum toxin injections. Results: Good cosmetic results were achieved for both patients. The side effects during and after treatment were mild pain and localized bruising; these symptoms resolved within several days without further treatment. Conclusion: Intradermal botulinum toxin injection may be an effective treatment for refractory erythema and rosacea flushing that deserves further study in a larger patient population.<\/jats:p>","DOI":"10.1159\/000368773","type":"journal-article","created":{"date-parts":[[2015,3,3]],"date-time":"2015-03-03T09:01:10Z","timestamp":1425373270000},"page":"299-301","source":"Crossref","is-referenced-by-count":61,"title":["Botulinum Toxin for the Treatment of Refractory Erythema and Flushing of Rosacea"],"prefix":"10.1159","volume":"230","author":[{"given":"Kui Young","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moo Yeol","family":"Hyun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Se Yeong","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beom Joon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myeung Nam","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang Kwun","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2015,3,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.120625"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.04.017"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1983.01650270029012"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1982.tb00290.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1999.02744.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2011.2615"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3390\/toxins4100913"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1353\/pbm.1997.0032"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2009.02.003"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20010"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/mds.20066"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s10286-002-0026-x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3171\/2012.11.FOCUS12373"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/dsu.12057"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/drm\/article-pdf\/230\/4\/299\/3894456\/000368773.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/drm\/article-pdf\/230\/4\/299\/3894456\/000368773.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:54:28Z","timestamp":1745430868000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000368773"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":14,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2015,4,1]]},"published-print":{"date-parts":[[2015,4,30]]}},"URL":"https:\/\/doi.org\/10.1159\/000368773","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}