{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:17:48Z","timestamp":1787314668803,"version":"build-2736575974"},"reference-count":16,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dig Surg"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; This study analyzed the patient survival outcomes following the resection of hepatocellular carcinoma (HCC) metachronous adrenal metastasis (MAM) in patients who had undergone liver resection or liver transplantation (LT). &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Clinical results were analyzed retrospectively in 26 patients with MAM-HCC who underwent adrenalectomy. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The mean interval between initial surgery and adrenalectomy was significantly shorter in the resection group than in the LT group (18.3 \u00b1 14.4 vs. 42.6 \u00b1 13.8 months, p &lt; 0.001). Of 19 resected patients, four had adrenal metastases on the right side, 12 on the left side and three bilaterally, with a mean tumor diameter of 3.6 \u00b1 1.5 cm. Ten of these patients underwent open surgery and nine underwent laparoscopic surgery; all patients experienced recurrences within 18 months and 20.3% survived 5 years after adrenalectomy. Of 7 patients who underwent LT, four had adrenal metastases on the right side and three on the left side, with a mean tumor diameter of 3.4 \u00b1 1.8 cm. Six of these patients underwent open surgery and one underwent laparoscopic surgery. Five-year recurrence and patient survival rates after adrenalectomy were 28.6 and 85.7%, respectively. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; Adrenalectomy is indicated in patients with isolated MAM-HCC. Comparisons with other locoregional treatment modalities and multicenter studies with additional patients are needed to validate the role of adrenalectomy.<\/jats:p>","DOI":"10.1159\/000370078","type":"journal-article","created":{"date-parts":[[2015,1,7]],"date-time":"2015-01-07T05:02:17Z","timestamp":1420606937000},"page":"428-435","source":"Crossref","is-referenced-by-count":18,"title":["Resection of Metachronous Adrenal Metastasis after Liver Resection and Transplantation for Hepatocellular Carcinoma"],"prefix":"10.1159","volume":"31","author":[{"given":"Tae-Yong","family":"Ha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chul-Soo","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki-Hun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Joo","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deok-Bog","family":"Moon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gi-Won","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Hwan","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gil-Chun","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Gyu","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2015,1,7]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2011.01.005"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25960"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/jso.20773"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s005950200210"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2013.08.068"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-012-1533-0"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyi020"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2010.04.002"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.141.8.771"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159\/000111705"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S1072-7515(02)01226-7"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyq055"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-012-2553-4"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.08.1752"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2009.02.018"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2011.52.1.199"}],"container-title":["Digestive Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/370078","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/370078","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T14:09:03Z","timestamp":1745417343000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000370078"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":16,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2015,2,1]]},"published-print":{"date-parts":[[2015,2,12]]}},"URL":"https:\/\/doi.org\/10.1159\/000370078","archive":["Portico"],"relation":{},"ISSN":["0253-4886","1421-9883"],"issn-type":[{"value":"0253-4886","type":"print"},{"value":"1421-9883","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}