{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T09:06:11Z","timestamp":1789203971596,"version":"build-2803163510"},"reference-count":10,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ORL"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Bisphosphonates are widely used for the treatment of osteoporosis and other bone-degrading disorders; however, bisphosphonate therapy is an important risk factor for osteonecrosis of the jaws. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; We report a rare case of bisphosphonate-related osteonecrosis of the palatal torus. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The patient was a 72-year-old woman with osteoporosis who had received 35 mg alendronate sodium hydrate once every week for 6 years. She had a 2-month history of oral pain because of intractable mucositis and ulceration of the palatal torus, with no history of malignant disease, radiation therapy, chemotherapy, steroid use, or recent dentoalveolar surgery. A CT scan showed a bony prominence at the midportion of the hard palate with erosion of its cortex. Her condition was diagnosed as stage 2 bisphosphonate-related osteonecrosis of the jaw caused by trauma, and she was advised to discontinue alendronate. She was prescribed oral antibiotics for 5 days and an oral antibacterial rinse. The mucositis with ulceration healed in approximately 10 weeks, but left a small scar. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; Although osteonecrosis of the palatal torus associated with bisphosphonate use is a rare condition, otolaryngologists should consider this condition in the differential diagnosis of intractable ulceration of the hard palate.<\/jats:p>","DOI":"10.1159\/000370120","type":"journal-article","created":{"date-parts":[[2015,1,23]],"date-time":"2015-01-23T08:58:32Z","timestamp":1422003512000},"page":"353-356","source":"Crossref","is-referenced-by-count":9,"title":["Bisphosphonate-Related Osteonecrosis of the Palatal Torus"],"prefix":"10.1159","volume":"76","author":[{"given":"Kenichi","family":"Kaneko","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruo","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2015,1,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.99.132"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(03)00720-1"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e318093ed70"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2010.01.007"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2006.10.061"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2009.01.009"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2005.07.010"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1159\/000350674"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1159\/000106451"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2009.03.050"}],"container-title":["ORL"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/370120","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/370120","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:09:22Z","timestamp":1745431762000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000370120"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":10,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2015,2,1]]},"published-print":{"date-parts":[[2015,2,5]]}},"URL":"https:\/\/doi.org\/10.1159\/000370120","archive":["Portico"],"relation":{},"ISSN":["0301-1569","1423-0275"],"issn-type":[{"value":"0301-1569","type":"print"},{"value":"1423-0275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}