{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T18:07:13Z","timestamp":1787508433934,"version":"build-2736575974"},"reference-count":20,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecol Obstet Invest"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; The aim of this study is to identify the inflammatory markers which predict a tubo-ovarian abscess (TOA) in the most accurate way. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; This study involves 312 women. Preoperative inflammatory markers in the study group were compared with those in the healthy control group to identify the most efficient predictor of TOA with a high sensitivity and specificity. The recommended cutoff values of the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), white blood cell count, and red cell distribution width were determined using receiver operating characteristic curve (ROC) analyses. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The area under the curve (AUC = 0.99) in the ROC analysis was found to be statistically significant for NLR (p &lt; 0.001) with a cutoff value of \u22654.15 (95% CI 0.97-1.00, sensitivity 95.2%, specificity 99.4%). The positive predictive value of NLR was 99.2%, and the negative predictive value was 96.7% (p &lt; 0.001). The recommended threshold for PLR was found to be 164.37 (AUC = 0.95, 95% CI 0.93-0.98, sensitivity 86.7%, specificity 92%), and the cutoff point of the white blood cell count in the ROC analysis was 9.55 \u00d7 10&lt;sup&gt;3&lt;\/sup&gt;\/\u03bcl (AUC = 0.90, 95% CI 0.87-0.95, sensitivity 78.68%, specificity 96.68%). &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Preoperative NLR and PLR improve the predictive value of serum markers for the presence of TOA.<\/jats:p>","DOI":"10.1159\/000371762","type":"journal-article","created":{"date-parts":[[2015,2,16]],"date-time":"2015-02-16T05:59:18Z","timestamp":1424066358000},"page":"234-239","source":"Crossref","is-referenced-by-count":31,"title":["Preoperative Neutrophil-to-Lymphocyte Ratio Has a Better Predictive Capacity in Diagnosing Tubo-Ovarian Abscess"],"prefix":"10.1159","volume":"80","author":[{"given":"Melahat","family":"Yildirim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esengul","family":"Turkyilmaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayse Filiz","family":"Avsar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2015,2,14]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/01.olq.0000175375.60973.cb"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159\/000358393"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159\/000362232"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2010.02.033"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1177\/1076029613485283"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.21669"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1361087"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S52501"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2013.12.001"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2014.01.026"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i45.8398"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1080\/1064744042000210366"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2003.11.036"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1084\/jem.174.4.785"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1080\/02841859509173418"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2013.07.017"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-012-2600-3"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111\/jog.12189"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2012.06.004"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2012-0795"}],"container-title":["Gynecologic and Obstetric Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/371762","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/371762","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/371762","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T14:16:08Z","timestamp":1745417768000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000371762"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":20,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2015,12,1]]},"published-print":{"date-parts":[[2015,12,10]]}},"URL":"https:\/\/doi.org\/10.1159\/000371762","archive":["Portico"],"relation":{},"ISSN":["0378-7346","1423-002X"],"issn-type":[{"value":"0378-7346","type":"print"},{"value":"1423-002X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}