{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T00:15:03Z","timestamp":1784852103504,"version":"3.55.0"},"reference-count":13,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2015,1,24]],"date-time":"2015-01-24T00:00:00Z","timestamp":1422057600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},{"start":{"date-parts":[[2015,1,24]],"date-time":"2015-01-24T00:00:00Z","timestamp":1422057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Ophthalmol"],"abstract":"<jats:p>We describe the cases of 2 autistic children with ophthalmic and systemic manifestations of vitamin A deficiency due to food faddism. Although vitamin A deficiency is common in the developing world, reports in developed societies are rare. Our patients presented over a 1-year period. The patients were 14 and 13 years old at the time of presentation and were both found to have marked features of vitamin A deficiency related to unusual dietary habits. Anterior segment signs of xerophthalmia were present in both patients. In addition, patient 1 showed evidence of a rod-predominant retinopathy, which resolved with vitamin A supplementation. Due to its rare occurrence, hypovitaminosis A must be highlighted and anticipated in this cohort.<\/jats:p>","DOI":"10.1159\/000373921","type":"journal-article","created":{"date-parts":[[2015,1,26]],"date-time":"2015-01-26T08:00:46Z","timestamp":1422259246000},"page":"24-29","source":"Crossref","is-referenced-by-count":31,"title":["Ophthalmic Manifestations of Vitamin A and D Deficiency in Two Autistic Teenagers: Case Reports and a Review of the Literature"],"prefix":"10.1159","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3968-4855","authenticated-orcid":false,"given":"Emma","family":"Duignan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Kenna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosemarie","family":"Watson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Fitzsimon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donal","family":"Brosnahan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2015,1,24]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.116.3.392"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1177\/0883073809333541"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3928\/01913913-20100318-04"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1177\/0148607111436280"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1177\/0148607193017003284"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2214.2006.00586.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2011.126"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3180959a5d"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2004.12.003"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/760695"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2006.00261.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2014.17"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2014.02.020"}],"container-title":["Case Reports in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/373921","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/373921","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:36:34Z","timestamp":1745429794000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000373921"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,24]]},"references-count":13,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2015,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000373921","archive":["Portico"],"relation":{},"ISSN":["1663-2699"],"issn-type":[{"value":"1663-2699","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,24]]}}}