{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:31:26Z","timestamp":1745469086792,"version":"3.40.4"},"reference-count":18,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiology"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objectives:&lt;\/i&gt;&lt;\/b&gt; Depression is associated with poor prognosis in patients with cardiovascular disease (CVD). We hypothesized that depressive symptoms at discharge from a cardiac rehabilitation program are associated with an increased risk of future CVD-related hospitalizations. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; We examined 486 CVD patients (mean age = 59.8 \u00b1 11.2) who enrolled in a comprehensive 3-month rehabilitation program and completed the depression subscale of the Hospital Anxiety and Depression Scale (HADS-D). At follow-up we evaluated the predictive value of depressive symptoms for CVD-related hospitalizations, controlling for sociodemographic factors, cardiovascular risk factors, and disease severity. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; During a mean follow-up of 41.5 \u00b1 15.6 months, 63 patients experienced a CVD-related hospitalization. The percentage of depressive patients (HADS-D \u22658) decreased from 16.9% at rehabilitation entry to 10.7% at discharge. Depressive symptoms at discharge from rehabilitation were a significant predictor of outcome (HR 1.32, 95% CI 1.09-1.60; p = 0.004). Patients with clinically relevant depressive symptoms at discharge had a 2.5-fold increased relative risk of poor cardiac prognosis compared to patients without clinically relevant depressive symptoms independently of other prognostic variables. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; In patients with CVD, depressive symptoms at discharge from rehabilitation indicated a poor cardiac prognosis.<\/jats:p>","DOI":"10.1159\/000375231","type":"journal-article","created":{"date-parts":[[2015,4,9]],"date-time":"2015-04-09T21:02:46Z","timestamp":1428613366000},"page":"80-85","source":"Crossref","is-referenced-by-count":8,"title":["Depressive Symptoms at Discharge from Rehabilitation Predict Future Cardiovascular-Related Hospitalizations"],"prefix":"10.1159","volume":"131","author":[{"given":"Fiorenza Angela","family":"Meyer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Hugentobler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefanie","family":"Stauber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Wilhelm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hansj\u00f6rg","family":"Znoj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"von K\u00e4nel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2015,4,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.2000.2294"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm316"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.4414\/smw.2012.13502"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/01.psy.0000146332.53619.b2"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/01.psy.0000146294.82810.9c"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0b013e318291d798"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2007.03.026"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2011.02.013"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/01.psy.0000133362.75075.a6"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/HCR.0b013e3182779b88"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3999(01)00296-3"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1406"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/01.psy.0000127692.23278.a9"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-1-29"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.190769"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.17.1878"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1161\/hc0902.104707"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2007.06091492"}],"container-title":["Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/375231","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/375231","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/375231","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:40:18Z","timestamp":1745430018000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000375231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":18,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2015,5,1]]},"published-print":{"date-parts":[[2015,5,27]]}},"URL":"https:\/\/doi.org\/10.1159\/000375231","archive":["Portico"],"relation":{},"ISSN":["0008-6312","1421-9751"],"issn-type":[{"type":"print","value":"0008-6312"},{"type":"electronic","value":"1421-9751"}],"subject":[],"published":{"date-parts":[[2015]]}}}