{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T01:18:28Z","timestamp":1791249508566,"version":"4.1.0"},"reference-count":54,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Chemotherapy"],"published-print":{"date-parts":[[2014]]},"abstract":"<b><i>Aims:<\/i><\/b> We compared the prevalence of extended-spectrum beta-lactamase (ESBL) producers in the faecal samples of 1,109 healthy individuals screened for employment purposes and in 531 asymptomatic individuals applying for long-term care (LTC). <b><i>Methods:<\/i><\/b> Eosin-methylene blue agar plates supplemented with 2 mg\/l cefotaxime were used to determine which individuals were ESBL producers. ESBL phenotype was confirmed by double-disk synergy test and ESBL genes were identified by sequencing. ESBL producers were characterized by co-resistance and integron carriage. <b><i>Results:<\/i><\/b> ESBL producers were more frequent in the LTC applicants than in the employment screening individuals (7.2 vs. 2.0%; p < 0.0001), with 43 <i>Escherichia coli<\/i>, 18 <i>Klebsiella pneumoniae<\/i>, 1 <i>Klebsiella oxytoca<\/i> and 1 <i>Proteus mirabilis<\/i> being found. In the employment screening individuals, only <i>E. coli<\/i> was found. Most ESBL genes (79.4%, 50\/63) were <i>bla<\/i><sub>CTX-M<\/sub> type; <i>bla<\/i><sub>CTX-M-15<\/sub> was more frequent in the LTC applicants (p < 0.001). Regarding ESBL genes and integron diversity,<i> E. coli<\/i> isolates from the LTC applicants were more similar to <i>K. pneumoniae<\/i> than to <i>E. coli<\/i> from the employment screening individuals. <b><i>Conclusion:<\/i><\/b> These differences in the characteristics of ESBL producers may represent different sources of colonization. Most LTC applicants harboured <i>K. pneumoniae<\/i> or <i>E. coli<\/i> that were probably hospital-acquired whereas the <i>E. coli<\/i> isolates of many healthy individuals showed similarities to environmental <i>E. coli<\/i>.<\/jats:p>","DOI":"10.1159\/000375407","type":"journal-article","created":{"date-parts":[[2015,5,12]],"date-time":"2015-05-12T17:01:26Z","timestamp":1431450086000},"page":"239-249","source":"Crossref","is-referenced-by-count":14,"title":["Carriage Rates and Characteristics of<b> <\/b>Enterobacteriaceae Producing Extended-Spectrum Beta-Lactamases in Healthy Individuals: Comparison of Applicants for Long-Term Care and Individuals Screened for Employment Purposes"],"prefix":"10.1159","volume":"60","author":[{"given":"Fatemeh","family":"Ebrahimi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julianna","family":"M\u00f3zes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00falia","family":"M\u00e9sz\u00e1ros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1gnes","family":"Juh\u00e1sz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e1bor","family":"Kardos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2015,4,18]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn287"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkh424"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2006.08.011"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkl483"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkq004"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00023-13"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2004.07.004"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3109\/00365540903493715"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks214"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2008.03.005"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/19.24.6823"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2013.09.015"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/PL00011293"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.47.12.3724-3732.2003"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkm316"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.12.5715-5721.2004"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/S0923-2508(99)80057-6"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.67.1.445-448.2001"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkl527"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.6.1568-1574.2000"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa010315"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.66.10.4555-4558.2000"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkp194"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.2007.01692.x"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1590\/S0074-02762004000800010"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1007\/BF02930963"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.3201\/eid1106.041111"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks118"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8305.2011.00548.x"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00220-10"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks429"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-011-1202-5"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.05539-11"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn293"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2012.02.004"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01319-06"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1086\/421094"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.3109\/00365548.2011.632642"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.7.3062-3065.2005"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn380"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.2.500-510.2002"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2007.06.015"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2012.05.020"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1186\/1746-6148-8-21"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1556\/AMicr.60.2013.2.8"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.2.833-835.2005"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmm.2011.09.009"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0005958"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.01446-10"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2013.09.021"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.3201\/eid1806.111214"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02890-10"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.3201\/eid1707.110209"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.10.4769-4775.2004"}],"container-title":["Chemotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/375407","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/375407","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/375407","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T13:42:10Z","timestamp":1745415730000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000375407"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":54,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2015,5,1]]},"published-print":{"date-parts":[[2015,5,12]]}},"URL":"https:\/\/doi.org\/10.1159\/000375407","archive":["Portico"],"relation":{},"ISSN":["0009-3157","1421-9794"],"issn-type":[{"value":"0009-3157","type":"print"},{"value":"1421-9794","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}