{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T10:53:25Z","timestamp":1790420005846,"version":"4.1.0"},"reference-count":18,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2015,4,21]],"date-time":"2015-04-21T00:00:00Z","timestamp":1429574400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},{"start":{"date-parts":[[2015,4,21]],"date-time":"2015-04-21T00:00:00Z","timestamp":1429574400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Dermatol"],"abstract":"<jats:p>The authors report a case of sensorimotor polyneuropathy, diffuse cutaneous hyperpigmentation, skin sclerodermiform thickening and papular lesions in the infraclavicular and abdominal region. Besides weight loss, there were diabetes mellitus and hypothyroidism. The alterations were consistent with POEMS (&lt;under&gt;P&lt;\/under&gt;olyneuropathy, &lt;under&gt;O&lt;\/under&gt;rganomegaly, &lt;under&gt;E&lt;\/under&gt;ndocrinopathy, &lt;under&gt;M&lt;\/under&gt;onoclonal gammopathy and &lt;under&gt;S&lt;\/under&gt;kin changes) syndrome, which is a rare systemic disease with monoclonal proliferation of plasmacytes and slow progression. Cutaneous alterations are present in 68% of patients with diffuse cutaneous hyperpigmentation, plethora and acrocyanosis. Leukonychia, necrotizing vasculitis, hypertrichosis and cutaneous thickening of sclerodermiform type are also cited. The onset of multiple cutaneous angiomas in this syndrome has been observed in 24-44% of patients.<\/jats:p>","DOI":"10.1159\/000381302","type":"journal-article","created":{"date-parts":[[2015,6,17]],"date-time":"2015-06-17T12:11:59Z","timestamp":1434543119000},"page":"61-69","source":"Crossref","is-referenced-by-count":11,"title":["Cutaneous Manifestations in POEMS Syndrome: Case Report and Review"],"prefix":"10.1159","volume":"7","author":[{"given":"Flauberto Sousa","family":"Marinho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Pirmez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renata","family":"Nogueira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tullia","family":"Cuzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celso Tavares","family":"Sodr\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1625-0760","authenticated-orcid":false,"given":"Marcia","family":"Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2015,4,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr.09.2010.3324"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.4996.802"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-198007000-00006"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2007.07.004"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-84842007000100018"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.33.583"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.43.1082"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-07-2299"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.4067\/S0034-98872004000400011"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962011000600016"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.100"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.2001.01246-2.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/16.10.2105"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2008.02997.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2008.02241.x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.4103\/0973-1482.87016"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.63.3.385"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-12-5045"}],"container-title":["Case Reports in Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/381302","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/381302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:52:45Z","timestamp":1745430765000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000381302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,21]]},"references-count":18,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2015,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000381302","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.5241787","asserted-by":"subject"}]},"ISSN":["1662-6567"],"issn-type":[{"value":"1662-6567","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,21]]}}}