{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T05:47:44Z","timestamp":1768715264076,"version":"3.49.0"},"reference-count":10,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2015,3,31]],"date-time":"2015-03-31T00:00:00Z","timestamp":1427760000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},{"start":{"date-parts":[[2015,3,31]],"date-time":"2015-03-31T00:00:00Z","timestamp":1427760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Oncol"],"abstract":"<jats:p>Swyer syndrome is caused by abnormal sex differentiation during the embryonic period, resulting in incomplete intrauterine masculinization and undifferentiated gonads. The current case report describes a patient with Swyer syndrome associated with stage 3 gonadal dysgerminoma who has survived for 23 years. At age 18, this patient sought assistance for primary amenorrhea from the Gynecological Services Department of the University of Bras\u00edlia Hospital. A physical examination revealed that the patient was at Tanner stage 4 with respect to axillary hair, breasts, and pubic hair; she presented with a eutrophic vagina and a small cervix. She was treated with a combination of estrogens and progestogens to induce cycling. Approximately 4 years later, a complex tumor was found and resected; a histopathological analysis revealed that this tumor was a right adnexal dysgerminoma with peritoneal affection. The patient was also subjected to chemotherapy. Her follow-up has continued to the present time, with no signs of tumor recurrence. In conclusion, this report describes an extremely rare case in which Swyer syndrome was associated with ovarian dysgerminoma; relative to similar patients, the described patient has survived for an unusually prolonged time.<\/jats:p>","DOI":"10.1159\/000381451","type":"journal-article","created":{"date-parts":[[2015,6,17]],"date-time":"2015-06-17T12:18:31Z","timestamp":1434543511000},"page":"179-184","source":"Crossref","is-referenced-by-count":15,"title":["A Case of Swyer Syndrome Associated with Advanced Gonadal Dysgerminoma Involving Long Survival"],"prefix":"10.1159","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1162-6263","authenticated-orcid":false,"given":"Salete","family":"Da Silva Rios","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabella Christina","family":"Mazzaro Monteiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larissa","family":"Gon\u00e7alves Braz dos Santos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natasha","family":"Garcia Caldas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana Carolina","family":"Rios Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliana","family":"Rios Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helena","family":"Spindola Camargo Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2015,3,31]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/MED.0000000000000113"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2006.03.004"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-27302005000100008"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1515\/jpem-2014-0071"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1297\/cpe.23.93"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.4103\/0971-9261.141995"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dei381"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpag.2013.07.001"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.04.043"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2014.05.003"}],"container-title":["Case Reports in Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/381451","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/381451","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:54:36Z","timestamp":1745430876000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000381451"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,31]]},"references-count":10,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2015,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000381451","archive":["Portico"],"relation":{},"ISSN":["1662-6575"],"issn-type":[{"value":"1662-6575","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,31]]}}}