{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:09:25Z","timestamp":1762506565170,"version":"3.40.4"},"reference-count":22,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecol Obstet Invest"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; The aim of this study was to determine the incidence, mortality rates and trends of vulvar and vaginal cancers in Poland. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Data were retrieved from the Polish National Cancer Registry. Age-standardised rates (ASRs) of cancer incidence and mortality were calculated by direct standardisation, and joinpoint regression was performed to describe the trends using the average annual percent change (AAPC). &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; From 1999 to 2012, the number of diagnosed cases of vulvar cancer was 5,958, and the ASRs of incidence varied from 0.99 to 1.18, with a significant trend towards a decrease (AAPC -0.78; p &lt; 0.05). The ASR of mortality varied from 0.39 to 0.62, with a slight but insignificant increase in trend (AAPC 0.72; p &gt; 0.05). The ASR of vaginal cancer incidence varied from 0.21 to 0.31, while the ASR of mortality ranged from 0.09 to 0.22. This study also proved a significantly falling trend in vaginal cancer mortality (AAPC -4.69; p &lt; 0.05) and a decreasing trend in vaginal cancer incidence (AAPC -1.67; p &gt; 0.05). &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; The rarity of vulvar and vaginal cancers as well as the decline in their incidence rates should not discourage further research on the epidemiology and treatment of these conditions.<\/jats:p>","DOI":"10.1159\/000381770","type":"journal-article","created":{"date-parts":[[2015,6,10]],"date-time":"2015-06-10T18:04:45Z","timestamp":1433959485000},"page":"240-245","source":"Crossref","is-referenced-by-count":4,"title":["Primary Vulvo-Vaginal Cancers: Trends in Incidence and Mortality in Poland (1999-2012)"],"prefix":"10.1159","volume":"80","author":[{"given":"Tomasz","family":"Banas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kzimierz","family":"Pitynski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Jach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Knafel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Artur","family":"Ludwin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grzegorz","family":"Juszczyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorota","family":"Nieweglowska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2015,6,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2009.20.1.8"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2005.10.007"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s004040000083"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2011.22.3.207"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-011-1850-9"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159\/000351309"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1159\/000343758"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1159\/000343230"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1159\/000357566"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159\/000336634"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1541-0420.2006.00528.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0258(20000215)19:3<335::AID-SIM336>3.0.CO;2-Z"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1997.441"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(01)00508-5"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-009-9418-8"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23759"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2007.11.011"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2009.08.011"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2009.20.4.232"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7109.646"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.2001.6502"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-12-1082"}],"container-title":["Gynecologic and Obstetric Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/381770","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/381770","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/381770","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:57:56Z","timestamp":1745431076000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000381770"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":22,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2015,12,1]]},"published-print":{"date-parts":[[2015,12,10]]}},"URL":"https:\/\/doi.org\/10.1159\/000381770","archive":["Portico"],"relation":{},"ISSN":["0378-7346","1423-002X"],"issn-type":[{"type":"print","value":"0378-7346"},{"type":"electronic","value":"1423-002X"}],"subject":[],"published":{"date-parts":[[2015]]}}}