{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T03:29:08Z","timestamp":1747193348950,"version":"3.40.5"},"reference-count":0,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestion"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Background: The combined effects of nutrient malabsorption and adiposity on vitamin D status are unclear in pediatric malabsorption syndromes. Aim: To determine the relationship between adiposity and serum 25-hydroxyvitamin D (25(OH)D) in malabsorption disorders. Methods: Prepubertal children of ages 3-12 with either lactose intolerance (LI) (n = 38, age 8.61 \u00b1 3.08, male\/female 19\/19), or celiac disease (CD) (n = 24) were compared to healthy controls (n = 49, age 7.95 \u00b1 2.64, male\/female 28\/21). A separate cohort of combined prepubertal and pubertal subjects with inflammatory bowel disease (IBD) (n = 59, age 16.4 \u00b1 2.2, male\/female 31\/27) were also compared to healthy controls (n = 116, male\/female 49\/67, age 14.6 \u00b1 4.4). Vitamin D deficiency was defined as 25(OH)D of &lt;50 nmol\/l, overweight as body mass index (BMI) of \u226585th but &lt;95th percentile, and obesity as BMI \u226595th percentile. Results: Among the controls, 25(OH)D was significantly higher in the normal-weight prepubertal controls vs. the overweight\/obese controls (p = 0.001), and similarly so for the combined cohort of prepubertal and pubertal controls (p = 0.031). In contrast, there was no significant difference in 25(OH)D concentration between the normal-weight vs. overweight\/obese patients with LI (p = 0.335), CD (p = 0.387), and IBD (p = 0.883). Conclusion: There is no association between adiposity and serum 25(OH)D in pediatric malabsorption syndromes.<\/jats:p>","DOI":"10.1159\/000381895","type":"journal-article","created":{"date-parts":[[2015,6,17]],"date-time":"2015-06-17T12:11:39Z","timestamp":1434543099000},"page":"1-7","source":"Crossref","is-referenced-by-count":6,"title":["Vitamin D Status and Adiposity in Pediatric Malabsorption Syndromes"],"prefix":"10.1159","volume":"92","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2212-0276","authenticated-orcid":false,"given":"Benjamin Udoka","family":"Nwosu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louise","family":"Maranda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2015,5,30]]},"container-title":["Digestion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/dig\/article-pdf\/92\/1\/1\/4035546\/000381895.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/dig\/article-pdf\/92\/1\/1\/4035546\/000381895.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:59:10Z","timestamp":1745431150000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000381895"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":0,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2015,8,1]]},"published-print":{"date-parts":[[2015,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000381895","archive":["Portico"],"relation":{},"ISSN":["0012-2823","1421-9867"],"issn-type":[{"type":"print","value":"0012-2823"},{"type":"electronic","value":"1421-9867"}],"subject":[],"published":{"date-parts":[[2015]]}}}