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Karger AG","issue":"3","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Neurosurg"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Malignant rhabdoid tumor (MRT) is a highly malignant and aggressive tumor associated with the kidney that is mainly seen in children under 5 years old, resulting in a rapid fatal outcome. MRT invasion of the cervical vertebra is an extremely rare form of this malignancy. This study presents a case of MRT involving the C4 vertebra and its appendix. A 13-year-old girl was found to have vague neck pain and a mass in the left neck area of the mid-cervical spine. Percutaneous needle biopsy was performed and the histological and immunohistochemical analysis pointed towards a rhabdoid tumor. Chemotherapy and radiotherapy were performed, but the tumor mass progressively enlarged. Tumorectomy was conducted followed by another 6 courses of chemotherapy and &lt;sup&gt;125&lt;\/sup&gt;I radioactive seed implantation. Unfortunately, the C4 vertebra and its appendix were found to be abnormal 3 months after the end of therapy. The patient received an additional tumorectomy, internal fixation with C4 reconstruction by a combined anterior and posterior approach, and 6 courses of consolidation chemotherapy. She is still alive 40 months since the initial diagnosis and remains asymptomatic 31 months after the surgery.<\/jats:p>","DOI":"10.1159\/000430448","type":"journal-article","created":{"date-parts":[[2015,5,19]],"date-time":"2015-05-19T21:01:18Z","timestamp":1432069278000},"page":"173-178","source":"Crossref","is-referenced-by-count":7,"title":["Malignant Rhabdoid Tumor with Cervical Vertebra Involvement in a Teenage Child: Case Report and Review of the Literature"],"prefix":"10.1159","volume":"50","author":[{"given":"Yu","family":"Tang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Song","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jintao","family":"Qu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianru","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2015,5,14]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197805)41:5<1937::AID-CNCR2820410538>3.0.CO;2-U"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.4161\/cbt.8.5.7730"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.07.073"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1827.2006.01962.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S1092-9134(98)80038-5"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-200205000-00020"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19820601)49:11<2365::AID-CNCR2820491125>3.0.CO;2-I"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-200010000-00008"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2001.00407.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/dc.10040"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199410000-00005"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2840110315"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(88)90194-6"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19850615)55:12<2850::AID-CNCR2820551224>3.0.CO;2-U"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3109\/01913129609016337"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/BF00704307"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19830715)52:2<290::AID-CNCR2820520216>3.0.CO;2-L"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-198707000-00027"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1007\/s002470100501"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1159\/000107372"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1007\/s00256-006-0104-6"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e31822541a6"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199903000-00001"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1097\/00125480-200007030-00007"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2003.11.014"}],"container-title":["Pediatric Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/430448","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/430448","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/430448","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:06:02Z","timestamp":1745431562000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000430448"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":25,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2015,7,1]]},"published-print":{"date-parts":[[2015,7,7]]}},"URL":"https:\/\/doi.org\/10.1159\/000430448","archive":["Portico"],"relation":{},"ISSN":["1016-2291","1423-0305"],"issn-type":[{"value":"1016-2291","type":"print"},{"value":"1423-0305","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}