{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T03:29:23Z","timestamp":1747193363144,"version":"3.40.5"},"reference-count":18,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Laser-assisted liposuction (LAL) is currently widely used to reduce localized fat. A novel Nd:YAG laser that uses a wavelength of 1,444 nm, which is better absorbed by fat, has recently been introduced. In this study, we investigated the efficacy of 1,444-nm Nd:YAG LAL for the treatment of gynecomastia. &lt;b&gt;&lt;i&gt;Patients and Methods:&lt;\/i&gt;&lt;\/b&gt; Thirteen Korean male patients (20-28 years, mean age 23 years) diagnosed with gynecomastia were enrolled in this study. All patients were treated by LAL with 1,444-nm Nd:YAG laser (100 \u00b5s pulse width, 40 Hz frequency, 300 mJ pulse energy and 12 W power with continuous emission) after tumescent anesthetic infiltration and were then evaluated. Outcome was assessed using the following 4 methods: (1) clinical assessment with photographs obtained before and 12 weeks after LAL treatment, (2) comparison of pre- and postoperative patient chest circumferences, (3) computed tomography (CT) scans to evaluate changes in breast thickness and (4) a patient satisfaction survey at the end of the study. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; After 12 weeks, most patients (84.5%) showed an improvement greater than 50%. Mean chest circumference was significantly reduced from 109.6 \u00b1 8.2 to 101.2 \u00b1 4.4 cm 12 weeks after LAL (p &lt; 0.001). CT scans showed a significant reduction in mean breast thickness from 22.7 \u00b1 3.2 to 15.6 \u00b1 2.4 mm (p = 0.016). Side effects (pain, edema, numbness and ecchymosis) were minimal and disappeared shortly after the first manifestation. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Gynecomastia can be safely treated with 1,444-nm Nd:YAG LAL to reduce fatty tissue and total breast volume.<\/jats:p>","DOI":"10.1159\/000430494","type":"journal-article","created":{"date-parts":[[2015,7,14]],"date-time":"2015-07-14T21:02:19Z","timestamp":1436907739000},"page":"224-230","source":"Crossref","is-referenced-by-count":5,"title":["Laser-Assisted Liposuction Using the Novel 1,444-nm Nd:YAG Laser for the Treatment of Gynecomastia: A Pilot Study"],"prefix":"10.1159","volume":"231","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0137-6849","authenticated-orcid":false,"given":"Kwang Ho","family":"Yoo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jung Min","family":"Bae","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chae Young","family":"Won","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu Seok","family":"Chung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boncheol","family":"Goo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Kwan","family":"Rho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gyong Moon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jongwon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Byeong Heon","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beom Joon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2015,7,15]]},"reference":[{"doi-asserted-by":"publisher","key":"ref1","DOI":"10.1111\/j.1742-1241.2012.03010.x"},{"doi-asserted-by":"publisher","key":"ref2","DOI":"10.1177\/1457496913496359"},{"doi-asserted-by":"publisher","key":"ref3","DOI":"10.1097\/01.PRS.0000042146.40379.25"},{"doi-asserted-by":"publisher","key":"ref4","DOI":"10.1007\/s10103-011-1043-6"},{"doi-asserted-by":"publisher","key":"ref5","DOI":"10.1111\/j.1365-4632.2009.04231.x"},{"doi-asserted-by":"publisher","key":"ref6","DOI":"10.1002\/lsm.20393"},{"doi-asserted-by":"publisher","key":"ref7","DOI":"10.1002\/lsm.20786"},{"doi-asserted-by":"publisher","key":"ref8","DOI":"10.1055\/s-0031-1283051"},{"doi-asserted-by":"publisher","key":"ref9","DOI":"10.5978\/islsm.20.39"},{"doi-asserted-by":"publisher","key":"ref10","DOI":"10.1056\/NEJMcp070677"},{"doi-asserted-by":"publisher","key":"ref11","DOI":"10.1210\/jc.2010-1720"},{"doi-asserted-by":"publisher","key":"ref12","DOI":"10.1111\/j.1742-1241.2006.01095.x"},{"doi-asserted-by":"publisher","key":"ref13","DOI":"10.1007\/BF01571338"},{"doi-asserted-by":"publisher","key":"ref14","DOI":"10.1586\/erd.09.50"},{"doi-asserted-by":"publisher","key":"ref15","DOI":"10.1002\/lsm.20649"},{"doi-asserted-by":"publisher","key":"ref16","DOI":"10.1111\/j.1524-4725.2011.02168.x"},{"doi-asserted-by":"publisher","key":"ref17","DOI":"10.1007\/s10103-012-1100-9"},{"doi-asserted-by":"publisher","key":"ref18","DOI":"10.1111\/1346-8138.12225"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/430494","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/430494","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/430494","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:06:46Z","timestamp":1745431606000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000430494"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":18,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2015,9,1]]},"published-print":{"date-parts":[[2015,9,17]]}},"URL":"https:\/\/doi.org\/10.1159\/000430494","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"type":"print","value":"1018-8665"},{"type":"electronic","value":"1421-9832"}],"subject":[],"published":{"date-parts":[[2015]]}}}