{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T09:04:25Z","timestamp":1776503065363,"version":"3.51.2"},"reference-count":28,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respiration"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Age-associated changes in the pulmonary system could be detected with imaging techniques. Widespread use of lung ultrasonography (US) requires characterization of a normal pattern. &lt;b&gt;&lt;i&gt;Objectives:&lt;\/i&gt;&lt;\/b&gt; To compare US and computed tomography (CT) findings in healthy subjects undergoing both techniques (with CT as the gold standard). &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; We prospectively selected 59 subjects undergoing chest CT and US on the same day, without a history of smoking, respiratory symptoms, or known pulmonary pathologies. There were 44 patients in group 1 (age =60 years - elderly) and 15 patients in group 2 (age =50 years - young). Lung US was performed with a convex and a linear probe, and 10 chest areas per patient were analyzed. Convex and linear probe agreement was evaluated by means of the Cohen &amp;#954; statistic; Fisher's exact test was used to compare categorical variables between groups. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Isolated B-lines were frequent in both group 1 (54.5%) and group 2 (40.0%); the number of chest areas positive for B-lines increased with age (16.1% in group 1 vs. 5.3% in group 2, p = 0.0028). In group 2, we found that 37.5% of subjects with B-lines had at least 1 chest area with multiple B-lines, but only 2 subjects had 2 or more. Moreover, in group 1 the chest CT documented a reticular pattern (2.3%), areas of increased density (9.1%), ground glass (6.8%), cysts (2.3%), bronchiectasis (22.7%), and bronchial thickening (6.8%); in group 2, only cysts (6.7%) and bronchiectasis (6.7%) were found. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; The senile lung is characterized by mild changes on CT and US. Chest areas positive for B-lines increase with age, and focal multiple B-lines can be found. However, diffuse patterns, especially in symptomatic subjects, suggest a different diagnosis.<\/jats:p>","DOI":"10.1159\/000430994","type":"journal-article","created":{"date-parts":[[2015,6,4]],"date-time":"2015-06-04T08:32:28Z","timestamp":1433406748000},"page":"56-62","source":"Crossref","is-referenced-by-count":29,"title":["The Senile Lung as a Possible Source of Pitfalls on Chest Ultrasonography and Computed Tomography"],"prefix":"10.1159","volume":"90","author":[{"given":"Federica","family":"Ciccarese","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Maria","family":"Chiesa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Feletti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Vizioli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milena","family":"Pasquali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Forti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Zoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maurizio","family":"Zompatori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2015,6,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3003.1999.13a36.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S51152"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/path.4122"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2512081242"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2513-4"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159\/000357685"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.22225"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.180.2.1800513"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2006.02.013"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-2800"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2013.06.004"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1159\/000360770"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00021005"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201308-1483ST"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1093\/geronj\/38.3.307"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.10092307"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.214.3.r00mr05831"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097\/RTI.0b013e31825148c9"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/584793"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1186\/2110-5820-4-1"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2010.01885.x"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1186\/2049-6958-8-54"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1186\/2049-6958-8-55"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1159\/000368086"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2004.02.012"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keu033"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2011-201072"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1258\/ar.2012.120340"}],"container-title":["Respiration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/430994","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/430994","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:09:26Z","timestamp":1745431766000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000430994"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":28,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2015,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000430994","archive":["Portico"],"relation":{},"ISSN":["0025-7931","1423-0356"],"issn-type":[{"value":"0025-7931","type":"print"},{"value":"1423-0356","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}