{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T17:15:01Z","timestamp":1779297301883,"version":"3.51.4"},"reference-count":17,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmologica"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Purpose:&lt;\/i&gt;&lt;\/b&gt; The effects of oxygen supplementation status and other clinical risk factors on the development of severe retinopathy of prematurity (ROP) were evaluated. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Clinical records of 143 newborn infants with a gestational age of 32 weeks or less were reviewed. Severe ROP was diagnosed when photocoagulation due to progression to stage 3 was identified or when \u2018plus disease' developed. The factors were evaluated with univariate and multivariate logistic regression analyses between the groups with severe (n = 24) and non-severe (n = 119) ROP. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Gestational age, birth weight, duration of oxygen supplementation, duration of directional positive air pressure and maximum fraction of inspiratory oxygen (FiO&lt;sub&gt;2&lt;\/sub&gt;) were significantly associated with severe ROP in the univariate analyses. In the multivariate analysis, a longer duration of oxygen supplementation and a higher maximum FiO&lt;sub&gt;2&lt;\/sub&gt; were revealed as significant risk factors associated with severe ROP. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; Duration of oxygen supplementation and maximum FiO&lt;sub&gt;2&lt;\/sub&gt; required were important factors associated with severe ROP.<\/jats:p>","DOI":"10.1159\/000433565","type":"journal-article","created":{"date-parts":[[2015,6,18]],"date-time":"2015-06-18T21:01:58Z","timestamp":1434661318000},"page":"135-138","source":"Crossref","is-referenced-by-count":23,"title":["Evaluation of Oxygen Supplementation Status as a Risk Factor Associated with the Development of Severe Retinopathy of Prematurity"],"prefix":"10.1159","volume":"234","author":[{"given":"Hiroko","family":"Enomoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Miki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wataru","family":"Matsumiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Honda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2015,6,19]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60178-6"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2007.126508"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s12519-009-0058-6"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2009.04.018"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2009.263"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2010.01846.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000000314"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2012.12.155"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1302298"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159\/000360646"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-013-0986-y"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.123.7.991"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1208129"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.07.050"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2010.05.003"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3928\/01913913-20140220-05"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2014.09.017"}],"container-title":["Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/433565","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/433565","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/433565","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:15:41Z","timestamp":1745432141000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000433565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":17,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2015,10,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000433565","archive":["Portico"],"relation":{},"ISSN":["0030-3755","1423-0267"],"issn-type":[{"value":"0030-3755","type":"print"},{"value":"1423-0267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}