{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T23:21:13Z","timestamp":1790637673431,"version":"4.1.0"},"reference-count":48,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2015,9,30]],"date-time":"2015-09-30T00:00:00Z","timestamp":1443571200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},{"start":{"date-parts":[[2015,9,30]],"date-time":"2015-09-30T00:00:00Z","timestamp":1443571200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dement Geriatr Cogn Disord Extra"],"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; After hypertensive disorders of pregnancy, more subjective cognitive complaints and white matter lesions are reported compared to women after normal pregnancies. Both have a causal relationship with Alzheimer's disease (AD). &lt;b&gt;&lt;i&gt;Aim:&lt;\/i&gt;&lt;\/b&gt; To investigate if women whose pregnancy was complicated by hypertensive disorders have an increased risk of AD. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; A case-control study in women with AD from the Alzheimer Center of the VU University Medical Center Amsterdam and women without AD. Paper and telephone surveys were performed. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The response rate was 85.2%. No relation between women with (n = 104) and without AD (n = 129) reporting pregnancies complicated by hypertensive disorders (p = 0.11) was found. Women with early-onset AD reported hypertensive disorders of pregnancy more often (p = 0.02) compared to women with late-onset AD. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; A reported history of hypertensive disorders of pregnancy appears not to be associated with AD later in life.<\/jats:p>","DOI":"10.1159\/000439043","type":"journal-article","created":{"date-parts":[[2015,9,29]],"date-time":"2015-09-29T21:01:29Z","timestamp":1443560489000},"page":"375-385","source":"Crossref","is-referenced-by-count":25,"title":["Hypertensive Disorders of Pregnancy Appear Not to Be Associated with Alzheimer's Disease Later in Life"],"prefix":"10.1159","volume":"5","author":[{"given":"Carolien N.H.","family":"Abheiden","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"van Doornik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annet M.","family":"Aukes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wiesje M.","family":"van der Flier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Scheltens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christianne J.M.","family":"de Groot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2015,9,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-002-1406-3"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0029-7844(03)00475-7"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60736-4"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2009.02382.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)17987-2"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2005.11.032"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60279-6"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2393-13-126"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.02.016"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39335.385301.BE"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(00)70521-7"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0b013e3180a6f094"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1515\/CCLM.2011.764"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.semnephrol.2010.10.010"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.06.044"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1080\/01674820802546212"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2014.01.042"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2013.06.003"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.12.033"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2012.03406.x"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000162"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2014.02.031"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1002\/gps.3765"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000242734.16663.09"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1097\/00019442-200508000-00005"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1159\/000124750"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2011.666"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1427.007"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1017\/S0959259812000172"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(200002)47:2<145::AID-ANA3>3.3.CO;2-G"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1002\/ana.10294"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1159\/000350317"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1002\/1531-8249(199912)46:6<827::AID-ANA4>3.3.CO;2-8"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.44.7.1246"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1159\/000026235"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.26.7.1293"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-8301.2009.00294.x"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2000.tb06349.x"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2012.07.065"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2012.3740"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2009.10.010"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwm139"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2007.09.038"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1081\/PRG-100104165"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-2010-1265"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3008808"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1006\/abio.1998.2933"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1016\/j.micron.2008.10.002"}],"container-title":["Dementia and Geriatric Cognitive Disorders Extra"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/439043","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/439043","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/439043","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:46:20Z","timestamp":1745430380000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000439043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,30]]},"references-count":48,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2015,12,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000439043","archive":["Portico"],"relation":{},"ISSN":["1664-5464"],"issn-type":[{"value":"1664-5464","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,30]]}}}