{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T06:23:37Z","timestamp":1792304617063,"version":"4.4.0"},"reference-count":20,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acta Cytologica"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objective:&lt;\/i&gt;&lt;\/b&gt; A malignant mixed m\u00fcllerian tumor (MMMT) is a high-grade neoplasm commonly arising from the uterus. Patients present with bleeding and a mass protruding from the cervix. This study was designed to correlate Papanicolaou (Pap) smear findings with histological findings in women diagnosed with MMMT. &lt;b&gt;&lt;i&gt;Study Design:&lt;\/i&gt;&lt;\/b&gt; Women diagnosed with MMMT were identified. Preoperative Pap tests were correlated with histological findings. Statistical analysis was performed to assess associations between abnormal Pap tests and histological findings. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Forty patients with MMMT were included in the study. Age ranged from 37-85 years and tumor size ranged from 1.2 to 21 cm. In presurgical Pap tests (4 conventional and 36 liquid based), 11 smears (27.5%) were diagnosed as negative, 5 (12.5%) as atypical squamous cells of undetermined significance, 6 (15%) as atypical glandular cells, 16 (40%) as malignant and 2 (5%) as high-grade squamous intraepithelial lesion. Malignant cells detected on Pap smears showed a strong correlation with endocervical involvement by MMMT (p = 0.002). Larger tumors were more likely to involve the cervix (p = 0.0115). &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; The Pap test can predict cervical involvement by MMMT. On Pap smears, MMMT cells showed no correlation with other adverse histological features (lymphovascular invasion, myoinvasion or adnexal involvement).<\/jats:p>","DOI":"10.1159\/000439159","type":"journal-article","created":{"date-parts":[[2015,8,28]],"date-time":"2015-08-28T21:01:25Z","timestamp":1440795685000},"page":"319-324","source":"Crossref","is-referenced-by-count":6,"title":["Atypical Findings on Cervicovaginal Smears Correlate with Cervical Involvement by Malignant Mixed M\u00fcllerian Tumors of the Uterus"],"prefix":"10.1159","volume":"59","author":[{"given":"Krisztina Z.","family":"Hanley","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriela","family":"Oprea-Ilies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Ormenisan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shabnam","family":"Seydafkan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina B.","family":"Mosunjac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2015,8,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2006.05.009"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1998.4941"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1997.4827"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20000615)88:12<2782::AID-CNCR17>3.0.CO;2-K"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(03)01561-X"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1309\/KUA1FQ3BQRC8YG4V"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/dc.22910"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/0090-8258(85)90122-2"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/00004347-199807000-00004"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/dc.21681"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1053\/ejso.2000.1104"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1159\/000327864"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1159\/000324052"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1309\/AJCPLFBK1A2XJDQI"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1002\/dc.2840080108"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/dc.10276"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2303.2010.00793.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2303.2008.00621.x"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1159\/000326386"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0339(200010)23:4<260::AID-DC9>3.0.CO;2-Y"}],"container-title":["Acta Cytologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/439159","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/439159","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/439159","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:47:42Z","timestamp":1745430462000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000439159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":20,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2015,8,1]]},"published-print":{"date-parts":[[2015,10,23]]}},"URL":"https:\/\/doi.org\/10.1159\/000439159","archive":["Portico"],"relation":{},"ISSN":["0001-5547","1938-2650"],"issn-type":[{"value":"0001-5547","type":"print"},{"value":"1938-2650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}