{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T21:24:19Z","timestamp":1775856259233,"version":"3.50.1"},"reference-count":14,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Appendage Disord"],"published-print":{"date-parts":[[2015]]},"abstract":"<b><i>Purpose:<\/i><\/b> The aim of this study was to assess the efficacy and tolerability of a combination noncorticosteroid, antiinflammatory\/antifungal shampoo versus 1% ketoconazole shampoo in the treatment of mild-to-moderate scalp seborrheic dermatitis (SD). <b><i>Procedures:<\/i><\/b> Twenty patients were randomized to using the combination shampoo (group A, 10 patients) or the 1% ketoconazole shampoo (group B, 10 patients) 3 times a week every other day for 8 weeks. Efficacy was evaluated by measuring the degree of scaling and pruritus by clinical and trichoscopic examination using a 4-point scale. Additionally, a physician global assessment (PGA) was assessed at the end of the study. <b><i>Results:<\/i><\/b> At 4 weeks, there was a significant reduction of scaling from baseline for both groups, while pruritus showed a significant reduction only for group A. After 8 weeks, there was a significant reduction of scaling and pruritus for both groups. PGA showed a complete response in 90% of the cases in both groups. <b><i>Conclusions:<\/i><\/b> The results of our study demonstrate that the combination noncorticosteroid, antiinflammatory\/antifungal shampoo represents an alternative approach to standard topical treatment for scalp SD. A noncorticosteroid shampoo may be equally safe and effective as ketoconazole shampoo for scalp SD, and trichoscopy provides accurate and reliable quantifiable data to assist in therapeutic monitoring.<\/jats:p>","DOI":"10.1159\/000439354","type":"journal-article","created":{"date-parts":[[2015,10,16]],"date-time":"2015-10-16T21:01:22Z","timestamp":1445029282000},"page":"126-130","source":"Crossref","is-referenced-by-count":13,"title":["Noncorticosteroid Combination Shampoo versus 1% Ketoconazole Shampoo for the Management of Mild-to-Moderate Seborrheic Dermatitis of the Scalp: Results from a Randomized, Investigator-Single-Blind Trial Using Clinical and Trichoscopic Evaluation"],"prefix":"10.1159","volume":"1","author":[{"given":"Federica","family":"Dall''Oglio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Lacarrubba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna Elisa","family":"Verz\u00ec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Micali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2015,10,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2004.00693.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10570.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2013.01.001"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jidsymp.5650048"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1825"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009446.pub2"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008138.pub3"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2007.02404.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2009.09.003"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2009.09.004"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2009.09.002"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200405030-00009"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.4103\/0974-7753.138588"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.147786"}],"container-title":["Skin Appendage Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/439354","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/439354","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:49:05Z","timestamp":1745430545000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000439354"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":14,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2016,2,1]]},"published-print":{"date-parts":[[2016,2,2]]}},"URL":"https:\/\/doi.org\/10.1159\/000439354","archive":["Portico"],"relation":{},"ISSN":["2296-9195","2296-9160"],"issn-type":[{"value":"2296-9195","type":"print"},{"value":"2296-9160","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}