{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T13:59:01Z","timestamp":1779112741990,"version":"3.51.4"},"reference-count":20,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urol Int"],"published-print":{"date-parts":[[2015]]},"abstract":"<b><i>Introduction:<\/i><\/b> Our aim was to describe the incidence and risk factors associated with extended-spectrum beta-lactamase (ESBL)-producing <i>Enterobacteriaceae<\/i> and their resistance rate in a urological ward. <b><i>Material and Methods:<\/i><\/b> We carried out a prospective observational study from November 2011 to December 2014, reviewing healthcare-associated infections (HAIs) in our department. We evaluated the infections caused by ESBL-producing <i>Enterobacteriaceae<\/i>. <b><i>Results:<\/i><\/b> The incidence of HAIs in our urology ward was 6.8%. <i>Enterobacteriaceae<\/i> including <i>Escherichia coli<\/i> (24.9%), <i>Klebsiella <\/i>spp. (12.1%), <i>Enterobacter <\/i>spp. (5.9%), <i>Morganella <\/i>spp. (1.5%), <i>Proteus <\/i>spp. (1.5%), and <i>Citrobacter <\/i>spp. (1.5%) represented 47.4% of the isolated pathogens. The percentage of ESBL-producing Enterobacteriaceae was 26.4. Risk factors associated with a higher incidence of ESBL-producing bacteria were prior urinary tract infection (UTI; p < 0.001), hypertension (p = 0.042), immunosuppression (p = 0.004), and urinary stone (p = 0.027). The multivariable analysis confirmed prior UTI, immunosuppression and urinary stone as risk factors. ESBL-producing strains showed resistance rates of 85.3% for fluoroquinolones and 11.8% for carbapenems. Moreover, 16.7% of ESBL-<i>Klebsiella<\/i> were resistant to carbapenems. <b><i>Conclusions:<\/i><\/b> ESBL-producing enterobacteria are associated with higher cross resistance to antibiotics such as quinolones. Higher resistance rates are reported in ESBL-producing <i>Klebsiella<\/i>. Among patients admitted in a urology ward, risk factors for ESBL-producing strains were previous UTI, immunosuppression, and urinary stone.<\/jats:p>","DOI":"10.1159\/000439441","type":"journal-article","created":{"date-parts":[[2015,9,23]],"date-time":"2015-09-23T02:35:17Z","timestamp":1442975717000},"page":"288-292","source":"Crossref","is-referenced-by-count":15,"title":["Extended-Spectrum Beta-Lactamase-Producing Bacteria in a Urology Ward: Epidemiology, Risk Factors and Antimicrobial Susceptibility 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