{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T13:14:04Z","timestamp":1790514844271,"version":"4.1.0"},"reference-count":18,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respiration"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Pulmonary embolism (PE) is diagnosed either by ventilation\/perfusion (V\/Q) scintigraphy or pulmonary CT angiography. One of the imaging methods used in nuclear medicine is hybrid SPECT\/CT scintigraphy. &lt;b&gt;&lt;i&gt;Objectives:&lt;\/i&gt;&lt;\/b&gt; The aim of this study was to evaluate the utility of SPECT\/CT(Q) scintigraphy in the diagnosis of PE and to compare SPECT\/CT(Q) with planar(Q) and SPECT(Q) methods. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; The study group consisted of 109 consecutive patients suspected of having PE referred for performing lung scintigraphy. The inclusion criteria were: performance of perfusion planar, SPECT and SPECT\/CT scans; availability of clinical data covering a 6-month follow-up period, and D-dimer level testing. The number of eligible patients was 84. PE was reported in patients with at least 1 segmental or 2 subsegmental perfusion defects without parenchymal abnormalities on CT scans. PE was excluded when there was a normal perfusion pattern or perfusion defects were caused by lung parenchymal abnormalities or were not arranged in accordance with the pulmonary vasculature. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Twenty-six patients (31%) had a final diagnosis of PE. The sensitivity and specificity values of each method were as follows: planar(Q) 73 and 43%, SPECT(Q) 88 and 47% and SPECT\/CT(Q) 100 and 83%. SPECT\/CT(Q) yielded a significantly higher diagnostic accuracy than planar(Q) (p &lt; 0.001) and SPECT(Q) (p &lt; 0.001) scans. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; We conclude that hybrid SPECT\/CT(Q) imaging has a high diagnostic efficacy in the diagnosis of PE. Lung perfusion scintigraphy performed with a hybrid SPECT\/CT device has a significantly higher sensitivity and specificity than scanning performed with the planar or SPECT technique.<\/jats:p>","DOI":"10.1159\/000439543","type":"journal-article","created":{"date-parts":[[2015,9,29]],"date-time":"2015-09-29T21:08:24Z","timestamp":1443560904000},"page":"393-401","source":"Crossref","is-referenced-by-count":39,"title":["The Utility of Hybrid SPECT\/CT Lung Perfusion Scintigraphy in Pulmonary Embolism Diagnosis"],"prefix":"10.1159","volume":"90","author":[{"given":"Andrzej","family":"Mazurek","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miroslaw","family":"Dziuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewa","family":"Witkowska-Patena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislaw","family":"Piszczek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Gizewska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2015,9,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1699-0463.1998.tb01360.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1160\/TH07-03-0212"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-009-1169-y"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.mednuc.2010.10.003"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/MNM.0b013e3282f258ef"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0146-6453(99)00006-8"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2008.01980.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.108.061606"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.2012.02939.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-144-3-200602070-00004"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/00006231-200211000-00011"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097\/MNM.0b013e3283336747"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-0361"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn310"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1990.03440200057023"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1159\/000365817"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1378\/chest.13-2090"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(00)00493-9"}],"container-title":["Respiration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/439543","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/439543","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/439543","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:50:33Z","timestamp":1745430633000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000439543"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":18,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2015,11,1]]},"published-print":{"date-parts":[[2015,11,25]]}},"URL":"https:\/\/doi.org\/10.1159\/000439543","archive":["Portico"],"relation":{},"ISSN":["0025-7931","1423-0356"],"issn-type":[{"value":"0025-7931","type":"print"},{"value":"1423-0356","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}