{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T14:25:34Z","timestamp":1780151134514,"version":"3.54.0"},"reference-count":18,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2015,11,17]],"date-time":"2015-11-17T00:00:00Z","timestamp":1447718400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2015,11,17]],"date-time":"2015-11-17T00:00:00Z","timestamp":1447718400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiology"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objectives:&lt;\/i&gt;&lt;\/b&gt; Heterotaxy syndrome is a recognized risk factor for surgical cardiac interventions. We evaluated the early- and middle-term results of a surgical intervention for patients with heterotaxy syndrome. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; A total of 42 patients with heterotaxy syndrome were enrolled (September 2008 to March 2015). Left and right atrial isomerism were identified in 26% (11 out of 42) and 74% of patients (31 out of 42), respectively. The median age of the patients at the time of surgery was 6.8 months (range: 5 days to 22.3 years). Biventricular repair was completed in 3 patients with left atrial isomerism. Seventeen out of 39 patients who were scheduled for single ventricular repair completed a modified Fontan procedure. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The hospital mortality rate was 4.7% (2 out of 42). Another 5 deaths occurred in the remaining survivors following hospital discharge with a follow-up duration of 45.8 \u00b1 23.6 months (range: 13-111 months). The 1-year and 5-year survival rates were 88.1% (37\/42) and 83.3% (35\/42), respectively. Univariate analysis and multivariate analysis identified pulmonary venous obstruction and atrioventricular valve replacement as additional risk factors for mortality. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; Right ventricular bypass surgery remains the preferred palliative procedure for patients with heterotaxy syndrome. Based on the current results, the early- and middle-term outcomes are satisfactory.<\/jats:p>","DOI":"10.1159\/000440947","type":"journal-article","created":{"date-parts":[[2015,11,16]],"date-time":"2015-11-16T22:01:26Z","timestamp":1447711286000},"page":"141-146","source":"Crossref","is-referenced-by-count":18,"title":["Early- and Middle-Term Surgical Outcomes in Patients with Heterotaxy Syndrome"],"prefix":"10.1159","volume":"133","author":[{"given":"Weidan","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hujun","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengchun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuansheng","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minghui","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinxin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2015,11,17]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.72.1205"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/00125817-200005000-00002"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2008.05.059"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2007.12.032"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-12-0957"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.07.053"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(90)90543-A"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(02)04124-3"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(93)91018-D"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.76.2.298"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2012.06.031"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8191.2009.00818.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1177\/021849230601400610"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00062-X"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2008.10.027"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezs594"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2009.02.060"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(01)02699-6"}],"container-title":["Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/440947","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/440947","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/440947","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:55:11Z","timestamp":1745430911000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000440947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,17]]},"references-count":18,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2016,2,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000440947","archive":["Portico"],"relation":{},"ISSN":["0008-6312","1421-9751"],"issn-type":[{"value":"0008-6312","type":"print"},{"value":"1421-9751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11,17]]}}}