{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:16:11Z","timestamp":1759331771782,"version":"3.40.4"},"reference-count":18,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2015,12,4]],"date-time":"2015-12-04T00:00:00Z","timestamp":1449187200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2015,12,4]],"date-time":"2015-12-04T00:00:00Z","timestamp":1449187200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmologica"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Purpose:&lt;\/i&gt;&lt;\/b&gt; To study the clinical and microbiological spectrum of endophthalmitis with emphasis on clinical features, visual outcomes and risks of surgical complications. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; A prospective observational study was conducted between 2012 and 2013 in a specific region in Denmark. Patients were clinically examined before, during and after surgical intervention for endophthalmitis. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Fifty eyes with endophthalmitis were included. Endophthalmitis after cataract surgery (post-cataract), anti-VEGF (vascular endothelial growth factor) intravitreal injections (post-injection) and cases of endogenous endophthalmitis were responsible for 40, 28 and 18% of all cases, respectively. There was no difference in the microbiological spectrum in post-cataract patients and post-injection patients, but patients with post-cataract endophthalmitis presented statistically significantly more frequently with hypopyon and fibrin in the anterior chamber. Between 20 and 25% of post-cataract and post-injection endophthalmitis patients developed a surgical complication after primary surgical intervention for endophthalmitis, and this was statistically significantly associated with a poor visual outcome. There was no statistically significant difference in the risk of surgical complications in phakic and pseudophakic eyes with post-injection endophthalmitis. Of the 8 patients with endogenous endophthalmitis, 67% developed a surgical complication, and these patients had a high mortality. The visual outcome in the most common types of endophthalmitis was good, with 60% of post-cataract patients achieving a visual outcome \u22650.5, and 64% of post-injection patients only had a mild vision loss (1-14 ETDRS letters) or even gained vision. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; The endophthalmitis cases had a broad clinical spectrum. Surprisingly, endogenous endophthalmitis accounted for almost one fifth of all cases. Patients with post-cataract endophthalmitis had a clinically different presentation than patients with post-injection endophthalmitis. In general, the bacteria were low-virulent and the visual outcomes good, but a substantial part of the patients developed a surgical complication which was associated with a poor visual outcome.<\/jats:p>","DOI":"10.1159\/000441662","type":"journal-article","created":{"date-parts":[[2015,12,3]],"date-time":"2015-12-03T22:01:21Z","timestamp":1449180081000},"page":"26-33","source":"Crossref","is-referenced-by-count":5,"title":["A Prospective Study on the Clinical and Microbiological Spectrum of Endophthalmitis in a Specific Region in Denmark"],"prefix":"10.1159","volume":"235","author":[{"given":"S\u00f8ren","family":"Solborg Bjerrum","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan","family":"Hamoudi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Friis-M\u00f8ller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morten","family":"la Cour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2015,12,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-014-2820-2"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-014-2644-0"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12576"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(98)96000-6"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2005.01.011"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(03)00202-2"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1995.01100120009001"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.02.032"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000000071"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2011-301439"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa042760"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e318221594a"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0b013e3182205996"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s40135-013-0033-1"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000000011"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2015.04.036"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2009.03.049"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.82.9.1078"}],"container-title":["Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/441662","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/441662","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/441662","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:02:58Z","timestamp":1745431378000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000441662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,4]]},"references-count":18,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2016,1,1]]},"published-print":{"date-parts":[[2016,1,12]]}},"URL":"https:\/\/doi.org\/10.1159\/000441662","archive":["Portico"],"relation":{},"ISSN":["0030-3755","1423-0267"],"issn-type":[{"type":"print","value":"0030-3755"},{"type":"electronic","value":"1423-0267"}],"subject":[],"published":{"date-parts":[[2015,12,4]]}}}