{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T17:20:29Z","timestamp":1763140829873,"version":"3.40.4"},"reference-count":62,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Obes Facts"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objective: &lt;\/i&gt;&lt;\/b&gt;The metabolic and cardiovascular risk of obesity is predominantly defined through the amount of intra-abdominal fat (IAF). Regarding this risk and the benefits of weight reduction gender-specific differences have been described. The aim of this study was to examine the gender-specific relationship between IAF assessed via ultrasound and the cardiometabolic risk profile in extremely obese adolescents before and after weight loss. &lt;b&gt;&lt;i&gt;Methods: &lt;\/i&gt;&lt;\/b&gt;In 107 consecutively admitted adolescents (n = 59 girls, mean age 15.4 \u00b1 2.6 years boys and 15.1 \u00b1 2.1 years girls, mean BMI z-score 3.2 \u00b1 0.6 boys and 3.5 \u00b1 0.6 girls) anthropometric and fasting laboratory chemical parameters were measured before and after an in-patient long-term therapy (mean durance 5.6 \u00b1 2.3 months). IAF was determined by measuring the intra-abdominal depth (IAD) via ultrasound. &lt;b&gt;&lt;i&gt;Results: &lt;\/i&gt;&lt;\/b&gt;IAD was higher in boys as compared to girls (58.0 \u00b1 22.4 mm vs. 51.3 \u00b1 16.0 mm). IAD values were positively associated with BMI-z scores, waist circumferences, HOMA-IR and serum levels of &amp;#947;GT, hs-CRP and IL-6 in both genders. In boys, but not in girls, IAD was significantly correlated with systolic and diastolic blood pressure, serum levels of triglycerides, ALT as well as adiponectin and HDL-cholesterol. After a marked mean weight loss of -27.1 \u00b1 16.2 kg (-20.1 \u00b1 7.9%) in boys and of -20.5 \u00b1 11.5 kg (-17.3 \u00b1 7.1%) in girls, IAD decreased by -20.7 \u00b1 16.2 mm (--32.4 \u00b1 16.9%) in boys and by -18.4 \u00b1 12,7 mm (-34.3 \u00b1 18.4%) in girls, resulting in more pronounced ameliorations of cardiovascular risk factors in boys than in girls. &lt;b&gt;&lt;i&gt;Conclusions: &lt;\/i&gt;&lt;\/b&gt;The present study indicates that IAF assessed by ultrasound is a good indicator for the cardiometabolic risk factor profile in extremely obese adolescents. Associations between IAF and risk factors are more pronounced in boys than in girls.<\/jats:p>","DOI":"10.1159\/000443690","type":"journal-article","created":{"date-parts":[[2016,4,9]],"date-time":"2016-04-09T02:55:55Z","timestamp":1460170555000},"page":"121-137","source":"Crossref","is-referenced-by-count":5,"title":["Sonographically Assessed Intra-Abdominal Fat And Cardiometabolic Risk Factors in Adolescents with Extreme 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