{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T20:13:16Z","timestamp":1781381596396,"version":"3.54.1"},"reference-count":20,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecol Obstet Invest"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background\/Aims:&lt;\/i&gt;&lt;\/b&gt; We aimed at performing a systematic review to determine the diagnostic accuracy of three-dimensional (3D) hysterosalpingo-contrast-sonography (HyCoSy) for detecting tubal occlusion. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; A systematic review in Medline database search from January 1989 to October 2015 to identify relevant studies evaluating 3D-HyCoSy. Eligibility criteria were studies assessing the role of 3D-HyCoSy for diagnosing tubal occlusion in infertile women. Index test was 3D-HyCoSy. Reference standard was laparoscopy with dye test or X-ray hysterosalpingography. Quality was assessed using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and Quality Assessment of Diagnostic Accuracy Studies-2 tool. Pooled sensitivity and specificity for the method were estimated. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; A total number of 88 papers were identified. After exclusions, nine studies were ultimately included. Pooled estimated sensitivity was 98% (95% CI 91-100) with a moderate heterogeneity (I&lt;sup&gt;2&lt;\/sup&gt;: 64.8%, 95% CI 39.6-89.9; and Cochran Q 22.7, p &lt; 0.001). Pooled estimated specificity was 90% (95% CI 83-95) with significant heterogeneity (I&lt;sup&gt;2&lt;\/sup&gt;: 80.3%, 95% CI 68.1-92.5; and Cochran Q 40.6, p &lt; 0.001). Positive likelihood ratio was 10.3 (95% CI 5.6-18.7) and negative likelihood ratio was 0.02 (95% CI 0.00-0.21). &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; 3D-HyCoSy is an accurate test for diagnosing tubal occlusion in women with infertility.<\/jats:p>","DOI":"10.1159\/000443955","type":"journal-article","created":{"date-parts":[[2016,1,29]],"date-time":"2016-01-29T22:01:16Z","timestamp":1454104876000},"page":"289-295","source":"Crossref","is-referenced-by-count":34,"title":["Three-Dimensional Hysterosalpingo-Contrast-Sonography for the Assessment of Tubal Patency in Women with Infertility: A Systematic Review with Meta-Analysis"],"prefix":"10.1159","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9700-0853","authenticated-orcid":false,"given":"Juan Luis","family":"Alc\u00e1zar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Txanton","family":"Martinez-Astorquiza Corral","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Orozco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime","family":"Dominguez-Piriz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leire","family":"Juez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tania","family":"Errasti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2016,1,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2011.02.054"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0096(199611\/12)24:9<523::AID-JCU6>3.0.CO;2-P"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2010.07.018"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.4293\/108680811X13176785203923"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deu024"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2000.00302.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/uog.7442"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-155-8-201110180-00009"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.327.7414.557"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2005.01.016"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/uog.11200"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-0705.2000.00327.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-813552"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/j.0001-6349.2005.00797.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2006.10.010"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/uog.11085"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.7863\/ultra.32.7.1233"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/S1001-9294(15)30014-6"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)57781-4"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/jog.12728"}],"container-title":["Gynecologic and Obstetric Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/443955","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/443955","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/443955","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:42:48Z","timestamp":1745430168000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000443955"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":20,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2016,7,6]]}},"URL":"https:\/\/doi.org\/10.1159\/000443955","archive":["Portico"],"relation":{},"ISSN":["0378-7346","1423-002X"],"issn-type":[{"value":"0378-7346","type":"print"},{"value":"1423-002X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}