{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T20:34:43Z","timestamp":1776803683354,"version":"3.51.2"},"reference-count":15,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urol Int"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; We investigated the efficacy of desmopressin in elderly patients with nocturnal polyuria (NP) to evaluate its effects on sleep quality. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Patients with NP (defined as the nighttime urine production &gt;33% of total 24-hour urine volume determined from a frequency-volume chart) were recruited. Desmopressin (0.2 mg) was treated orally at bedtime for 12 weeks. The participants completed the Medical Outcomes Study (MOS) Sleep Scale. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The mean patient age was 62.7 \u00b1 13.0 (range 42-78 years). The mean symptom duration was 42.2 \u00b1 39.7 months. The number of nocturia episodes (from 3.49 \u00b1 1.83 to 2.03 \u00b1 1.35, p = 0.01), nocturnal urine volume (p = 0.01), NP index (p = 0.01), and nocturia index (p = 0.01) decreased significantly after treatment with desmopressin. Among the MOS Sleep Scale categories, hours slept\/night (p = 0.042), shortness of breath (p = 0.019), and adequacy of sleep (p = 0.001) changed significantly with a decrease in the number of nocturia episodes. Adverse events were mild. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; Desmopressin is an effective treatment for NP and improved sleep quality in elderly men.<\/jats:p>","DOI":"10.1159\/000443968","type":"journal-article","created":{"date-parts":[[2016,2,2]],"date-time":"2016-02-02T23:00:48Z","timestamp":1454454048000},"page":"438-442","source":"Crossref","is-referenced-by-count":6,"title":["Efficacy of Desmopressin to Treat Nocturnal Polyuria in Elderly Men: Effects on Sleep Quality"],"prefix":"10.1159","volume":"96","author":[{"given":"Sun-Ouck","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ho Song","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dongdeuk","family":"Kwon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2016,2,3]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2001.116091"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)67961-X"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/51A.3.M108"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1614.2004.01444.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200565010-00008"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410x.1999.00012.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410X.2002.02791.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2007.01.027"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.03.095"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000136203.76320.f6"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.5213\/inj.2011.15.2.82"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3109\/02813439209014044"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2004.00791.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1520-6777(1999)18:6<559::AID-NAU6>3.0.CO;2-D"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)00312-5"}],"container-title":["Urologia Internationalis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/443968","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/443968","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/443968","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:42:59Z","timestamp":1745430179000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000443968"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":15,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2016,5,28]]},"published-print":{"date-parts":[[2016,5,24]]}},"URL":"https:\/\/doi.org\/10.1159\/000443968","archive":["Portico"],"relation":{},"ISSN":["0042-1138","1423-0399"],"issn-type":[{"value":"0042-1138","type":"print"},{"value":"1423-0399","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}