{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T03:29:55Z","timestamp":1747193395713,"version":"3.40.5"},"reference-count":13,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatology"],"published-print":{"date-parts":[[2016]]},"abstract":"<b><i>Objective:<\/i><\/b> Cranial magnetic resonance imaging (MRI) is associated with neurodevelopmental outcome in full-term infants with neonatal encephalopathy (NE) following presumed perinatal asphyxia. The aim of this study is to relate 2-dimensional measurements of the basal ganglia and thalami (BGT) and cerebellum in the first week after birth and after 3 months with neurodevelopmental outcome at 18 months. <b><i>Methods:<\/i><\/b> Retrospectively, 29 full-term infants with NE following presumed perinatal asphyxia who had a cranial MRI in the first week after birth were studied serially. One- and 2-dimensional measurements were obtained and related to different patterns of brain injury, and neurodevelopmental outcome at 18 months. A Griffiths developmental quotient <85 or cerebral palsy was considered adverse. <b><i>Results:<\/i><\/b> On the first MRI, the adverse outcome group showed increased basal ganglia width (42.1 \u00b1 0.1 vs. 40.3 \u00b1 0.3 mm, p < 0.001), thalamic width (40.3 \u00b1 0.1 vs. 39.3 \u00b1 1.0 mm, p < 0.001), and basal ganglia surface (1,230 \u00b1 21 vs. 1,199 \u00b1 36 mm<sup>2<\/sup>, p = 0.007) compared to the favorable outcome group. In the BGT lesions group, basal ganglia width and thalamic width were increased compared to the watershed infarction group (42.1 \u00b1 0.1 vs. 40.9 \u00b1 0.8 mm, p < 0.001, and 40.3 \u00b1 0.1 vs. 39.9 \u00b1 0.5 mm, p = 0.01, respectively). On the second MRI, cerebellar width was larger in the favorable outcome group (p = 0.025). There was a greater increase in dimensions between both MRI time points for basal ganglia width (p = 0.014), basal ganglia surface (p = 0.028) and thalamic width (p = 0.012) in the favorable outcome group. <b><i>Conclusions:<\/i><\/b> One- and 2-dimensional measurements for basal ganglia surface, BGT width and cerebellar width are associated with neurodevelopmental outcome at 18 months.<\/jats:p>","DOI":"10.1159\/000444121","type":"journal-article","created":{"date-parts":[[2016,3,11]],"date-time":"2016-03-11T22:01:41Z","timestamp":1457733701000},"page":"27-32","source":"Crossref","is-referenced-by-count":8,"title":["Serial 1- and 2-Dimensional Cerebral MRI Measurements in Full-Term Infants after Perinatal Asphyxia"],"prefix":"10.1159","volume":"110","author":[{"given":"Laura G.","family":"Spring in ''t Veld","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda S.","family":"de Vries","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Alderliesten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manon J.N.L.","family":"Benders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9284-1637","authenticated-orcid":false,"given":"Floris","family":"Groenendaal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2016,3,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12658-X"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2492071581"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-010-1692-9"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70295-9"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.11110213"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-010-0674-9"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/fn.75.3.F145"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31821f442d"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.12122"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2009.10.006"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159\/000348823"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-015-3665-8"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2012-301768"}],"container-title":["Neonatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/444121","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/444121","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/444121","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:44:37Z","timestamp":1745430277000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000444121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":13,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2016,6,17]]}},"URL":"https:\/\/doi.org\/10.1159\/000444121","archive":["Portico"],"relation":{},"ISSN":["1661-7800","1661-7819"],"issn-type":[{"type":"print","value":"1661-7800"},{"type":"electronic","value":"1661-7819"}],"subject":[],"published":{"date-parts":[[2016]]}}}