{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:31:53Z","timestamp":1745469113194,"version":"3.40.4"},"reference-count":5,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2016,2,26]],"date-time":"2016-02-26T00:00:00Z","timestamp":1456444800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2016,2,26]],"date-time":"2016-02-26T00:00:00Z","timestamp":1456444800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Ophthalmol"],"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Purpose:&lt;\/i&gt;&lt;\/b&gt; To describe a case of keratouveitis caused by &lt;i&gt;Euphorbia grandicornis&lt;\/i&gt; sap, that resolved with topic steroids. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; We report a case presentation of a patient with keratouveitis. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; A 70-year-old woman suffered from accidental ocular contact with &lt;i&gt;E. grandicornis&lt;\/i&gt; sap in her left eye. Two hours after the contact, she attended the clinic due to conjunctival hyperemia and pain. Best-corrected visual acuity (BCVA) was 20\/25. The toxic conjunctivitis was treated with topical lubricant and steroid. After 24 h, she presented blurred vision. BCVA was 20\/80. Toxic keratouveitis was diagnosed. Topical treatment with 1% cyclopentolate t.i.d., 5% sodium chloride, 1.14% dexamethasone phosphate each hour, and 4% sodium hyaluronate each hour was continued. Complete resolution was obtained 1 week later. &lt;i&gt;Euphorbia&lt;\/i&gt; sap content analysis was performed using dissolvent extraction spectrophotometry. Its contents included flavonoids, alkaloids, phenols and sesquiterpene lactones. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Corneal exposure to &lt;i&gt;E. grandicornis &lt;\/i&gt;sap is a cause of nonvisually threatening keratouveitis when adequately treated with corticosteroids.<\/jats:p>","DOI":"10.1159\/000444438","type":"journal-article","created":{"date-parts":[[2016,2,25]],"date-time":"2016-02-25T22:01:57Z","timestamp":1456437717000},"page":"125-129","source":"Crossref","is-referenced-by-count":2,"title":["Euphorbia grandicornis Sap Keratouveitis: A Case Report"],"prefix":"10.1159","volume":"7","author":[{"given":"Mar\u00eda","family":"G\u00f3mez-Valc\u00e1rcel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graciana","family":"Fuentes-P\u00e1ez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2016,2,26]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e31805444e5"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.118.1.13"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.80.9.823"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(01)01233-0"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2010.04.012"}],"container-title":["Case Reports in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/444438","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/444438","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/444438","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:47:56Z","timestamp":1745430476000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000444438"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,26]]},"references-count":5,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2016,4,28]]}},"URL":"https:\/\/doi.org\/10.1159\/000444438","archive":["Portico"],"relation":{},"ISSN":["1663-2699"],"issn-type":[{"type":"electronic","value":"1663-2699"}],"subject":[],"published":{"date-parts":[[2016,2,26]]}}}