{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T10:41:10Z","timestamp":1783420870636,"version":"3.54.6"},"reference-count":34,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"},{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Princ Pract"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objectives:&lt;\/i&gt;&lt;\/b&gt; To evaluate the analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block for patients undergoing laparoscopic cholecystectomy (LC). &lt;b&gt;&lt;i&gt;Materials and Methods:&lt;\/i&gt;&lt;\/b&gt; A systematic literature search was conducted to identify randomized controlled trials that compared ultrasound-guided TAP block with control for analgesia in adult patients undergoing LC. The original data were pooled for the meta-analysis using Review Manager 5. The main outcomes included postoperative pain intensity, opioid consumption, and adverse events. Out of a total of 77 trials, 7 were included. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Compared with control, ultrasound-guided TAP block reduced the following: (1) postoperative pain intensity (visual analog scale: 0-10) both at rest and on movement at 0, 2, 4, 8, and 24 h (at rest: mean difference, MD&lt;sub&gt;0 h&lt;\/sub&gt; = -2.19, 95% confidence interval, CI: -3.46 to -0.91, p = 0.0008; on movement: MD&lt;sub&gt;0 h&lt;\/sub&gt; = -2.67, 95% CI: -3.86 to -1.48, p &lt; 0.0001); (2) intraoperative fentanyl consumption (MD = -27.85 \u00b5g, 95% CI: -44.91 to -10.79, p = 0.001), and (3) morphine consumption in the recovery room (MD = -1.57 mg, 95% CI: -3.0 to -0.14, p = 0.03) and 0-24 h postoperatively. Fewer patients required analgesics in the recovery room when receiving TAP blocks (risk ratio, RR = 0.35, 95% CI: 0.20 to 0.62, p = 0.0003). TAP blocks also reduced postoperative nausea and vomiting (RR = 0.48, 95% CI: 0.28 to 0.81, p = 0.006). None of the studies reported symptoms of local anesthetic toxicity. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; In this study, the ultrasound-guided TAP block was an effective strategy for analgesia in patients undergoing LC.<\/jats:p>","DOI":"10.1159\/000444688","type":"journal-article","created":{"date-parts":[[2016,2,16]],"date-time":"2016-02-16T22:01:26Z","timestamp":1455660086000},"page":"237-246","source":"Crossref","is-referenced-by-count":74,"title":["Ultrasound-Guided Transversus Abdominis Plane Block for Analgesia in Laparoscopic Cholecystectomy: A Systematic Review and Meta-Analysis"],"prefix":"10.1159","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2879-1759","authenticated-orcid":false,"given":"Ke","family":"Peng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fu-hai","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua-yue","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shao-ru","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2016,2,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7689"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006231"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000094390.82352.cb"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-002-9121-2"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/ACO.0b013e328330373a"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/ca.20621"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000000066"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2012.09.012"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-1318.2012.03104.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2010.05.008"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007705.pub2"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2011.06855.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b2535"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e318169d03b"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0000000000000219"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2013.11.023"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.892055"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.4097\/kjae.2013.64.6.511"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.4097\/kjae.2010.58.4.362"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aep067"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(00)00406-1"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-199905000-00015"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.rapm.2007.11.009"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0b013e3181e66702"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aen344"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2044.2009.05933.x"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200604000-00030"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0b013e318244851b"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9185.98331"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aes279"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1007\/s12630-012-9729-1"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1016\/j.rapm.2005.10.006"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000290294.64090.f3"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0000000000000088"}],"container-title":["Medical Principles and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/444688","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/444688","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/444688","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:49:59Z","timestamp":1745430599000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000444688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":34,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2016,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000444688","archive":["Portico"],"relation":{},"ISSN":["1011-7571","1423-0151"],"issn-type":[{"value":"1011-7571","type":"print"},{"value":"1423-0151","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}