{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T23:16:27Z","timestamp":1780096587073,"version":"3.54.0"},"reference-count":10,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ORL"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Tinnitus is an annoying problem and until now there is no consensus on its treatment. &lt;b&gt;&lt;i&gt;Aims:&lt;\/i&gt;&lt;\/b&gt; In this prospective study, we evaluated the effectiveness of intratympanic lidocaine and dexamethasone (ITLD) injections for the management of subjective idiopathic tinnitus (SIT). &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; Forty patients with SIT attended the Department of Otorhinolaryngology, Tanta University Hospital, Egypt, between May 2013 and May 2014. The patients were categorized into two groups: group A included 20 patients treated with ITLD injection, and group B included 20 patients treated with intratympanic saline injection as a control. Intratympanic injections were performed four times within 4 weeks in a double-blind manner. At the end of the treatment program, we analyzed the improvement and worsening rates of tinnitus using the following parameters: tinnitus questionnaires, Tinnitus Handicap Index (THI), and loudness matching test. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The effectiveness rates of the ITLD group reported in the tinnitus questionnaires, the THI and the loudness matching test were 74.3% in all tests, compared to 26.7, 40.0 and 26.7%, respectively, in the saline group. There was a statistically significant difference between the groups within 2 months after injection. To analyze the therapeutic effect of ITLD on tinnitus of 6 months duration, the improvement rates reported in the tinnitus questionnaires, the THI and the loudness matching test were 78.5% in all tests in the ITLD group, compared to 40.0, 40.0 and 30.0%, respectively, in the saline group. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; There were statistically significant differences between both groups. ITLD seems to be effective for idiopathic tinnitus.<\/jats:p>","DOI":"10.1159\/000445774","type":"journal-article","created":{"date-parts":[[2016,5,31]],"date-time":"2016-05-31T21:33:32Z","timestamp":1464730412000},"page":"159-166","source":"Crossref","is-referenced-by-count":13,"title":["Tinnitus: Evaluation of Intratympanic Injection of Combined Lidocaine and Corticosteroids"],"prefix":"10.1159","volume":"78","author":[{"given":"Saad","family":"Elzayat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossam","family":"El-Sherif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Hegazy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takwa","family":"Gabr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdel-Rahman","family":"El-Tahan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2016,6,1]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200303000-00007"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3109\/00016483609123219"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0385-8146(84)80012-7"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100120304"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199907001-00001"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2004.03.004"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.131.2.113"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(96)70133-X"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1992.tb01835.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2008.05.019"}],"container-title":["ORL"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/445774","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/445774","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/445774","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:01:31Z","timestamp":1745431291000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000445774"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":10,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2016,6,22]]}},"URL":"https:\/\/doi.org\/10.1159\/000445774","archive":["Portico"],"relation":{},"ISSN":["0301-1569","1423-0275"],"issn-type":[{"value":"0301-1569","type":"print"},{"value":"1423-0275","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}