{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T18:56:30Z","timestamp":1760122590496,"version":"3.40.4"},"reference-count":38,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microb Physiol"],"published-print":{"date-parts":[[2016]]},"abstract":"Variation is a central trait of the polymorphic membrane protein (Pmp) family. The number of <i>pmp<\/i> coding sequences differs between <i>Chlamydia<\/i> species, but it is unknown whether the number of <i>pmp<\/i> coding sequences is constant within a <i>Chlamydia<\/i> species. The level of conservation of the Pmp proteins has previously only been determined for <i>Chlamydia trachomatis.<\/i> As different Pmp proteins might be indispensible for the pathogenesis of different <i>Chlamydia <\/i>species, this study investigated the conservation of Pmp proteins both within and across <i>C. trachomatis,<\/i><i>C. pneumoniae,<\/i><i>C. abortus,<\/i> and <i>C. psittaci.<\/i> The <i>pmp<\/i> coding sequences were annotated in 16 <i>C. trachomatis,<\/i> 6 <i>C. pneumoniae,<\/i> 2 <i>C. abortus,<\/i> and 16 <i>C. psittaci<\/i> genomes. The number and organization of polymorphic membrane coding sequences differed within and across the analyzed <i>Chlamydia <\/i>species. The length of coding sequences of <i>pmpA,<\/i><i>pmpB,<\/i> and <i>pmpH<\/i> was conserved among all analyzed genomes, while the length of <i>pmpE\/F<\/i> and <i>pmpG,<\/i> and remarkably also of the subtype <i>pmpD,<\/i> differed among the analyzed genomes. PmpD, PmpA, PmpH, and PmpA were the most conserved Pmp in <i>C. trachomatis,<\/i><i>C. pneumoniae,<\/i><i>C. abortus,<\/i> and <i>C. psittaci<\/i>, respectively. PmpB was the most conserved Pmp across the 4 analyzed <i>Chlamydia<\/i> species.<\/jats:p>","DOI":"10.1159\/000447092","type":"journal-article","created":{"date-parts":[[2016,7,27]],"date-time":"2016-07-27T21:02:28Z","timestamp":1469653348000},"page":"333-344","source":"Crossref","is-referenced-by-count":7,"title":["The Number, Organization, and Size of Polymorphic Membrane Protein Coding Sequences<b> <\/b>as well as the Most Conserved Pmp Protein Differ within and across <b><i>Chlamydia<\/i><\/b> Species"],"prefix":"10.1159","volume":"26","author":[{"given":"Sarah","family":"Van Lent","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather Huot","family":"Creasy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Garry 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