{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:10:08Z","timestamp":1745428208574,"version":"3.40.4"},"reference-count":13,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T00:00:00Z","timestamp":1469059200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T00:00:00Z","timestamp":1469059200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Ophthalmol"],"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Purpose:&lt;\/i&gt;&lt;\/b&gt; To report a rare case of keratitis infected by &lt;i&gt;Bipolaris hawaiiensis&lt;\/i&gt;. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; A patient who was diagnosed as fungal keratitis caused by &lt;i&gt;B. hawaiiensis&lt;\/i&gt; was retrospectively reviewed for history, clinical characteristics, risk factors, laboratory findings, treatments, and outcomes. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; A 63-year-old man with a history of trauma and saw dust in the left eye presented with a corneal ulcer. Eye examination revealed whitish infiltration with a feathery edge and small brownish deposits in the anterior stroma of the left cornea. Numerous septate hyphal fragments were detected in a corneal specimen, and nucleotide sequence analysis identified &lt;i&gt;B. hawaiiensis&lt;\/i&gt;. Treatment was started with 5% natamycin eyedrops and oral itraconazole. Subsequently, a corneal plaque developed which did not respond to medication and debridement. The patient underwent therapeutic penetrating keratoplasty. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; &lt;i&gt;B. hawaiiensis&lt;\/i&gt; is a rare cause of corneal phaeohyphomycosis. A brownish pigmented infiltration is an important diagnostic clue, however microbiologic studies are required to obtain a definite diagnosis. Although antifungal medication and debridement are the mainstay of most corneal fungal infection, therapeutic penetrating keratoplasty can prevent morbidity related to this fungal infection.<\/jats:p>","DOI":"10.1159\/000447737","type":"journal-article","created":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T21:01:25Z","timestamp":1469134885000},"page":"364-371","source":"Crossref","is-referenced-by-count":4,"title":["Corneal Phaeohyphomycosis Caused by &lt;b&gt;&lt;i&gt;Bipolaris hawaiiensis&lt;\/i&gt;&lt;\/b&gt;"],"prefix":"10.1159","volume":"7","author":[{"given":"Winai","family":"Chaidaroon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumet","family":"Supalaset","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Napaporn","family":"Tananuvat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nongnuch","family":"Vanittanakom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2016,7,21]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.4103\/0377-4929.41700"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ico.0000126435.25751.20"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200005000-00010"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/BF01716706"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)00079-2"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200208000-00004"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.86.11.1211"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.2307\/3758492"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-200103000-00012"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.144198"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-008-9144-x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1080\/02681218880000411"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01965-12"}],"container-title":["Case Reports in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/447737","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/447737","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/447737","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:56:03Z","timestamp":1745427363000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000447737"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,21]]},"references-count":13,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2016,8,28]]}},"URL":"https:\/\/doi.org\/10.1159\/000447737","archive":["Portico"],"relation":{},"ISSN":["1663-2699"],"issn-type":[{"type":"electronic","value":"1663-2699"}],"subject":[],"published":{"date-parts":[[2016,7,21]]}}}