{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T23:51:37Z","timestamp":1767829897655,"version":"3.49.0"},"reference-count":12,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2016,10,15]],"date-time":"2016-10-15T00:00:00Z","timestamp":1476489600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2016,10,15]],"date-time":"2016-10-15T00:00:00Z","timestamp":1476489600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ocul Oncol Pathol"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Purpose:&lt;\/i&gt;&lt;\/b&gt; To report a case of chronic eye pain as a presenting feature of choroidal metastasis from lung cancer. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; We report the case of a 58-year-old Caucasian woman with stage IV lung adenocarcinoma presenting with an 8-month history of left eye pain and blurred vision. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; The patient had previously consulted 14 ophthalmologists with varying diagnoses including posterior scleritis and trigeminal neuralgia. Visual acuity at presentation was 20\/20 in the right eye and 20\/80 in the left eye. Examination of the right eye was normal, while the left eye showed ill-defined flat yellow discoloration of the choroid with overlying shifting subretinal fluid. Ultrasonography demonstrated a dense choroidal thickening measuring 2.6 mm in size and showing subretinal fluid. Enhanced depth imaging optical coherence tomography revealed choroidal thickening with a \u2018lumpy bumpy' surface topography consistent with a metastatic choroidal tumor presumably from the patient's lung adenocarcinoma. Fine needle aspiration biopsy followed by treatment was recommended, but the patient declined and later succumbed to metastatic disease. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; We present a case of chronic eye pain associated with diffuse choroidal thickening from metastatic lung adenocarcinoma that was previously unrecognized and misdiagnosed. This case emphasizes the importance of recognizing pain as a presenting symptom of choroidal metastasis.<\/jats:p>","DOI":"10.1159\/000448720","type":"journal-article","created":{"date-parts":[[2016,10,14]],"date-time":"2016-10-14T21:01:24Z","timestamp":1476478884000},"page":"56-59","source":"Crossref","is-referenced-by-count":5,"title":["Unrelenting Ocular Pain as a Masquerading Symptom of Occult Choroidal Metastasis"],"prefix":"10.1159","volume":"3","author":[{"given":"Jordan D.","family":"Deaner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renelle","family":"Pointdujour-Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emil Anthony T.","family":"Say","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3288-3632","authenticated-orcid":false,"given":"Carol L.","family":"Shields","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2016,10,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(97)30148-1"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.06.015"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.07.014"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/eye.1997.72"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2012.12.004"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8619(03)00093-8"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2013.11.007"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)90543-2"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/00055735-199906000-00002"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000000288"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-013-9894-4"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-012-1972-1"}],"container-title":["Ocular Oncology and Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/448720","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/448720","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/448720","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:05:43Z","timestamp":1745427943000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000448720"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,15]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,1,19]]},"published-print":{"date-parts":[[2017,1,19]]}},"URL":"https:\/\/doi.org\/10.1159\/000448720","archive":["Portico"],"relation":{},"ISSN":["2296-4681","2296-4657"],"issn-type":[{"value":"2296-4681","type":"print"},{"value":"2296-4657","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,15]]}}}