{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T14:17:08Z","timestamp":1761401828772,"version":"3.40.4"},"reference-count":25,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2016,10,8]],"date-time":"2016-10-08T00:00:00Z","timestamp":1475884800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2016,10,8]],"date-time":"2016-10-08T00:00:00Z","timestamp":1475884800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cerebrovasc Dis Extra"],"abstract":"<b><i>Background and Purpose:<\/i><\/b> Following transient ischemic attack (TIA), there is increased risk for ischemic stroke. The American Heart Association recommends admission of patients with ABCD<sup>2<\/sup> scores \u22653 for observation, rapid performance of diagnostic tests, and potential acute intervention. We aimed to determine if there is a relationship between ABCD<sup>2<\/sup> scores, in-hospital ischemic events, and in-hospital treatments after TIA admission. <b><i>Methods:<\/i><\/b> We reviewed consecutive patients admitted between 2006 and 2011 following a TIA, defined as transient focal neurological symptoms attributed to a specific vascular distribution and lasting <24 h. Three interventions were prespecified: anticoagulation for atrial fibrillation, carotid or intracranial revascularization, and intravenous or intra-arterial reperfusion therapies. We compared rates of in-hospital recurrent TIA or ischemic stroke and the receipt of interventions among patients with low (<3) versus high (\u22653) ABCD<sup>2<\/sup> scores. <b><i>Results:<\/i><\/b> Of 249 patients, 11 patients (4.4%) had recurrent TIAs or strokes during their stay (8 TIAs, 3 strokes). All 11 had ABCD<sup>2<\/sup> scores \u22653, and no neurological events occurred in patients with lower scores (5.1 vs. 0%; p = 0.37). Twelve patients (4.8%) underwent revascularization for large artery stenosis, 16 (6.4%) were started on anticoagulants, and no patient received intravenous or intra-arterial reperfusion therapy. The ABCD<sup>2<\/sup> score was not associated with anticoagulation (p = 0.59) or revascularization (p = 0.20). <b><i>Conclusions:<\/i><\/b> Higher ABCD<sup>2<\/sup> scores may predict early ischemic events after TIA but do not predict the need for intervention. Outpatient evaluation for those with scores <3 would potentially have delayed revascularization or anticoagulant treatment in nearly one-fifth of \u2018low-risk' patients.<\/jats:p>","DOI":"10.1159\/000450692","type":"journal-article","created":{"date-parts":[[2016,10,7]],"date-time":"2016-10-07T21:02:55Z","timestamp":1475874175000},"page":"76-83","source":"Crossref","is-referenced-by-count":8,"title":["High ABCD2 Scores and In-Hospital Interventions following Transient Ischemic Attack"],"prefix":"10.1159","volume":"6","author":[{"given":"Shawna","family":"Cutting","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Regan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivien H.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shyam","family":"Prabhakaran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2016,10,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2007.08.016"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181a826ad"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.22.2901"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000134416.89389.9d"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181dad63e"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.101668"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60150-0"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.570010"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.192218"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2012.03858.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e31823d763f"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s12245-010-0176-x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.636506"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001780"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(10)70240-4"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.515817"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.108.521476"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2011.03428.x"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1159\/000360757"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.003077"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1159\/000352060"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2015.4949"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000002715"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000002614"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70248-X"}],"container-title":["Cerebrovascular Diseases Extra"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/450692","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/450692","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/450692","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:14:35Z","timestamp":1745428475000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000450692"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,8]]},"references-count":25,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2017,7,11]]}},"URL":"https:\/\/doi.org\/10.1159\/000450692","archive":["Portico"],"relation":{},"ISSN":["1664-5456"],"issn-type":[{"type":"electronic","value":"1664-5456"}],"subject":[],"published":{"date-parts":[[2016,10,8]]}}}