{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T03:14:04Z","timestamp":1770347644258,"version":"3.49.0"},"reference-count":0,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2016,10,22]],"date-time":"2016-10-22T00:00:00Z","timestamp":1477094400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2016,10,22]],"date-time":"2016-10-22T00:00:00Z","timestamp":1477094400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecol Obstet Invest"],"published-print":{"date-parts":[[2017]]},"abstract":"<b><i>Introduction:<\/i><\/b> This study evaluated the role of <sup>18<\/sup>F-fluorodeoxyglucose (FDG) positron emission tomography\/CT (PET\/CT) in the detection of lymph node metastases and the association between uterine maximum standardized uptake values (SUVmax) and the histopathological features in endometrial cancer patients. <b><i>Materials and Methods:<\/i><\/b> Patients with endometrioid endometrial cancer underwent preoperative <sup>18<\/sup>F-FDG PET\/CT imaging and were staged surgically. <sup>18<\/sup>F-FDG PET\/CT findings were compared with final pathology reports. Grade 3 histology or grade 2 histology with myometrial invasion \u226550% was established as a high risk feature. <b><i>Results:<\/i><\/b> One hundred and eleven patients were analysed. Sensitivity, specificity, accuracy, positive predictive value (PPV) and negative predictive value (NPV) of <sup>18<\/sup>F-FDG PET\/CT in the detection of lymph node metastasis in all patients (n = 111) were 67, 96, 93, 60 and 97%, respectively. In the high-risk group, sensitivity, specificity, accuracy, PPV and NPV of <sup>18<\/sup>F-FDG PET\/CT were 75, 92, 91, 60 and 96%, respectively. Uterine SUVmax was found to be associated with myometrial invasion, grade and cervical stromal involvement. <b><i>Conclusions:<\/i><\/b><sup>18<\/sup>F-FDG PET\/CT has limited sensitivity and accuracy in detecting lymph node metastasis. Therefore, as of now, it is not accepted as a modality that can replace lymphadenectomy. SUVmax values can predict high-risk factors.<\/jats:p>","DOI":"10.1159\/000452100","type":"journal-article","created":{"date-parts":[[2016,10,21]],"date-time":"2016-10-21T21:01:37Z","timestamp":1477083697000},"page":"340-348","source":"Crossref","is-referenced-by-count":13,"title":["Preoperative <sup>18<\/sup>F-Fluorodeoxyglucose Positron Emission Tomography\/CT in Prediction of Uterine Risk Factors and Lymph Node Metastasis: An Analysis of 111 Endometrioid Endometrial Cancer Patients"],"prefix":"10.1159","volume":"82","author":[{"given":"Bahar","family":"Konuralp Atakul","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salih","family":"Ta\u015fk\u0131n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c7i\u011fdem","family":"Soydal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yavuz Emre","family":"S\u00fck\u00fcr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alper","family":"Kahraman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazibe","family":"Koyuncu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erkan","family":"\u0130bi\u015f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Firat","family":"Ortac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2016,10,22]]},"container-title":["Gynecologic and Obstetric Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/452100","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/452100","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:18:32Z","timestamp":1745428712000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000452100"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,22]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2017,7,18]]},"published-print":{"date-parts":[[2017,7,20]]}},"URL":"https:\/\/doi.org\/10.1159\/000452100","archive":["Portico"],"relation":{},"ISSN":["0378-7346","1423-002X"],"issn-type":[{"value":"0378-7346","type":"print"},{"value":"1423-002X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,22]]}}}