{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:24:04Z","timestamp":1792092244634,"version":"4.4.0"},"reference-count":25,"publisher":"S. Karger AG","issue":"3-4","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur Neurol"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Purpose:&lt;\/i&gt;&lt;\/b&gt; To examine the efficacy of selective repetitive transcranial magnetic stimulation (rTMS) therapy guided by functional near-infrared spectroscopy (fNIRS) combined with intensive speech therapy (iST) on post-stroke patients with aphasia. &lt;b&gt;&lt;i&gt;Material and Methods:&lt;\/i&gt;&lt;\/b&gt; Eight right-handed patients with aphasia in the chronic stage after stroke were grouped into left and right hemisphere-activated for a language task based on pre-intervention fNIRS. Those with left hemisphere activation received 1-Hz TMS to the right inferior frontal gyrus (RtIFG; low-frequency rTMS [LFS] group), and those with right hemisphere activation received 10-Hz TMS to the RtIFG (high-frequency rTMS [HFS] group). The patients underwent an 11-day program of rTMS and iST. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Both groups showed a significant improvement in language function as measured by Standard Language Test of Aphasia (SLTA) total score at post-intervention relative to pre-intervention. Furthermore, the pre-to-post SLTA change scores were not statistically different between the groups. Comparison of pre- and post-intervention fNIRS revealed a resolution of the imbalance of interhemispheric inhibition in the LFS group and activation of the target hemisphere in the HFS group. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; The administration of fNIRS-guided selective rTMS therapy and iST to post-stroke patients with aphasia induced a significant improvement in language function, with both groups demonstrating a similar degree of improvement.<\/jats:p>","DOI":"10.1159\/000457901","type":"journal-article","created":{"date-parts":[[2017,2,8]],"date-time":"2017-02-08T07:59:30Z","timestamp":1486540770000},"page":"186-194","source":"Crossref","is-referenced-by-count":54,"title":["The Effect of Selective Transcranial Magnetic Stimulation with Functional Near-Infrared Spectroscopy and Intensive Speech Therapy on Individuals with Post-Stroke Aphasia"],"prefix":"10.1159","volume":"77","author":[{"given":"Takatoshi","family":"Hara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Abo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyohito","family":"Kakita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuyuki","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2017,2,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410380416"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1044\/jslhr.4101.172"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.111.000574"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.bandl.2011.07.005"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.bandl.2011.02.005"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn043"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1044\/jslhr.4101.172"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1159\/000338773"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007\/s12975-015-0417-7"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1177\/1545968314521009"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-007-0952-x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.11253\/ninchishinkeikagaku.12.27"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-5597(97)00096-8"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(87)90206-9"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.44.2.269"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2008.08.036"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.2496\/apr.4.638"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.597864"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2015.00236"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.27.5.897"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200408260-00011"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2006.01558.x"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.bandl.2006.02.002"},{"key":"ref24"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.2496\/hbfr.34.298"}],"container-title":["European Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/457901","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/457901","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/457901","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T13:32:31Z","timestamp":1745415151000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000457901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":25,"journal-issue":{"issue":"3-4","published-online":{"date-parts":[[2017,3,16]]}},"URL":"https:\/\/doi.org\/10.1159\/000457901","archive":["Portico"],"relation":{},"ISSN":["0014-3022","1421-9913"],"issn-type":[{"value":"0014-3022","type":"print"},{"value":"1421-9913","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}