{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:26:06Z","timestamp":1777868766203,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T00:00:00Z","timestamp":1502409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T00:00:00Z","timestamp":1502409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Enzyme"],"abstract":"<jats:p>Creatine kinase isoenzymes in sera and muscle biopsies obtained from 50 controls, 72\npatients with progressive muscular dystrophy (PMD), 68 patients with other neuromuscular\ndisorders, 17 carriers of Duchenne-type PMD and 15 patients with myocardial infarction were\nstudied. MB isoenzyme was detected in the sera of 58 patients with PMD and 56 out of 61 muscle\nbiopsies. The MB activity varied between 4 and 400IU\/1 or 3.4\u201422% of total activity. The MB\nactivity was demonstrated in a considerably smaller number of cases with polymyositis, dystrophic\nmyotonia and Kugelberg-Welander disease. The MB isoenzyme in sera of PMD persisted for many\nyears. It is admitted that the MB isoenzyme in the serum of patients with PMD originates chiefly\nfrom skeletal muscle.<\/jats:p>","DOI":"10.1159\/000458585","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T17:10:50Z","timestamp":1502471450000},"page":"238-245","source":"Crossref","is-referenced-by-count":19,"title":["Serum Creatine Kinase Isoenzymes in Progressive Muscular\nDystrophy"],"prefix":"10.1159","author":[{"given":"Elena","family":"Tzvetanova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2017,8,11]]},"container-title":["Enzyme"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000458585","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T12:39:23Z","timestamp":1777552763000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000458585"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,11]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000458585","archive":["Portico"],"relation":{},"ISSN":["0013-9432","2504-2564"],"issn-type":[{"value":"0013-9432","type":"print"},{"value":"2504-2564","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,11]]}}}