{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:26:20Z","timestamp":1777868780386,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T00:00:00Z","timestamp":1502409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T00:00:00Z","timestamp":1502409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Enzyme"],"abstract":"<jats:p>Changes in enzyme activity in human trichinosis have been studied. The\nactivities of 19 enzymes and some isoenzymes were investigated in 12 patients from the\n3rd to the 20th week. The activities of muscle-specific enzymes (CK, ALD and MK) were\ngreatly increased with peaks during the 4th week; activities returned to normal ranges\nduring the 7th and 8th weeks. Liver-specific enzymes (GTP, OCT, guanase, GLDH, SDH\nand MDH) and AP, ChE, ceruloplasmin remained within normal limits in all patients\nwith the exception of a child who died. An explanation of the origin of hyperenzymemia\nis proposed on the basis of these investigations. The data obtained support the proposition\nthat hyperenzymemia is of muscular origin and that the liver is seldom affected in case of\ntrichinosis.<\/jats:p>","DOI":"10.1159\/000458927","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T17:11:30Z","timestamp":1502471490000},"page":"117-122","source":"Crossref","is-referenced-by-count":1,"title":["Changes in Enzyme Activity in Human Trichinosis"],"prefix":"10.1159","author":[{"given":"E.","family":"Tzvetanova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2017,8,11]]},"container-title":["Enzyme"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000458927","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T12:40:56Z","timestamp":1777552856000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000458927"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,11]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000458927","archive":["Portico"],"relation":{},"ISSN":["0013-9432","2504-2564"],"issn-type":[{"value":"0013-9432","type":"print"},{"value":"2504-2564","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,11]]}}}