{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:26:27Z","timestamp":1777868787222,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T00:00:00Z","timestamp":1502409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T00:00:00Z","timestamp":1502409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Enzyme"],"abstract":"<jats:p>A review is made of the distribution and functions\nof cytochrome P450 in various tissues. \u2018Normal\u2019 levels\nof the enzyme are tabulated and factors inducing higher levels\nare discussed. Evidence suggestive of the existence of different\nspecies of the enzyme is discussed, as is the hypothesis that\ngenetically defective (or absent) isoenzymes of cytochrome\nP450 can provide an explanation for the clinical findings caused\nby the adrenogenital syndrome.<\/jats:p>","DOI":"10.1159\/000459009","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T17:11:42Z","timestamp":1502471502000},"page":"348-376","source":"Crossref","is-referenced-by-count":20,"title":["Biological Aspects of Cytochrome P450 and\nAssociated Hydroxylation Reactions"],"prefix":"10.1159","author":[{"given":"Rohan H.","family":"Wickramasinghe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2017,8,11]]},"container-title":["Enzyme"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000459009","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T12:41:29Z","timestamp":1777552889000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000459009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,11]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000459009","archive":["Portico"],"relation":{},"ISSN":["0013-9432","2504-2564"],"issn-type":[{"value":"0013-9432","type":"print"},{"value":"2504-2564","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,11]]}}}