{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:26:36Z","timestamp":1777868796810,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T00:00:00Z","timestamp":1502409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T00:00:00Z","timestamp":1502409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Enzyme"],"abstract":"<jats:p>The results of immunochemical studies performed in 6 cases of type II glycogenosis\n(1 classical form, Pompe\u2019s disease) and 5 atypical forms (2 juvenile, 3 adult) are\nreported. The use of antiacid \u03b1-1,4-glucosidase antibodies greatly improved the specificity of\nthe diagnostic tests for type II glycogenosis, particularly in fibroblasts, lymphocytes, and\nurine. The use of these antibodies permits the precise measurement of lysosomal enzymes and\nalso enables to demonstrate the activating influence of potassium chloride on urinary lysosomal\n\u03b1-1,4-glucosidase. The use of such specific antibodies should prove to be an aid in\ngenetic studies and allows a better understanding of the disease mechanism.<\/jats:p>","DOI":"10.1159\/000459173","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T17:12:20Z","timestamp":1502471540000},"page":"182-190","source":"Crossref","is-referenced-by-count":2,"title":["Immunochemical Studies of Human Acid\nAlpha-1,4-Glucosidase in Type II Glycogenosis"],"prefix":"10.1159","author":[{"given":"J.","family":"Bienvenu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Mathieu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2017,8,11]]},"container-title":["Enzyme"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000459173","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T12:42:32Z","timestamp":1777552952000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000459173"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,11]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000459173","archive":["Portico"],"relation":{},"ISSN":["0013-9432","2504-2564"],"issn-type":[{"value":"0013-9432","type":"print"},{"value":"2504-2564","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,11]]}}}