{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:49:31Z","timestamp":1790398171619,"version":"4.1.0"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T00:00:00Z","timestamp":1502409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T00:00:00Z","timestamp":1502409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Enzymol Biol Clin"],"abstract":"<jats:p>Some properties of human serum\nand human tissue adenosine deaminase have been studied. Normal and pathological human\nserum adenosine deaminase and normal human tissue adenosine deaminase show the\nsame activation energy values which are different\nfrom those found for the calf intestine enzyme. In the human species, but not\nin the bovine species, the serum enzyme differs from the tissue enzyme in pH optimum\nand relative substrate specificity for adenosine and 2\u2019deoxyadenosine. Temperature\nconversion factors for human serum and calf intestine adenosine deaminase\nhave also been calculated.<\/jats:p>","DOI":"10.1159\/000459567","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T17:13:07Z","timestamp":1502471587000},"page":"417-425","source":"Crossref","is-referenced-by-count":115,"title":["Temperature Conversion Factors, Activation Energy,\nRelative Substrate Specificity and Optimum pH of\nAdenosine Deaminase from Human Serum and Tissues"],"prefix":"10.1159","author":[{"given":"G.","family":"Giusti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Gakis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2017,8,11]]},"container-title":["Enzymologia biologica et clinica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000459567","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T12:44:48Z","timestamp":1777553088000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000459567"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,11]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000459567","archive":["Portico"],"relation":{},"ISSN":["0425-1423","2504-2572"],"issn-type":[{"value":"0425-1423","type":"print"},{"value":"2504-2572","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,11]]}}}