{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:17:17Z","timestamp":1777907837438,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T00:00:00Z","timestamp":1502409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T00:00:00Z","timestamp":1502409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Pharmacopsychiatry"],"abstract":"<jats:p>Orthodromic and antidromic conduction velocities were measured in the\ntail nerve of rats given lithium throughout life. Lithium at nontoxic levels failed to\ninfluence nerve conduction velocities. Lithium at toxic levels (2 X 2.5 mmol\/kg\/day for\n7 days) produced overt signs of lithium intoxication and reduced both orthodromic and\nantidromic nerve conduction velocities. The reductions in conduction velocities were\nrelated inversely to the level of lithium in serum and red blood cells. Conduction velocities\nreturned to normal levels after cessation of the toxic lithium treatment. The findings show\nlife-long administration of lithium at nontoxic levels to be without adverse effects on\nperipheral nerves in rats, while toxic lithium levels caused reversible impairment in conduction\nproperties in peripheral nerves.<\/jats:p>","DOI":"10.1159\/000468487","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T17:20:46Z","timestamp":1502472046000},"page":"129-137","source":"Crossref","is-referenced-by-count":2,"title":["Effects of Lithium on Rat Tail Nerve Conduction\nVelocity"],"prefix":"10.1159","author":[{"given":"Takashi","family":"Ebara","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Nakayama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saburo","family":"Otsuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shosuke","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2017,8,11]]},"container-title":["International Pharmacopsychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000468487","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:49:23Z","timestamp":1777643363000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000468487"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,11]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000468487","archive":["Portico"],"relation":{},"ISSN":["0020-8272","2504-2580"],"issn-type":[{"value":"0020-8272","type":"print"},{"value":"2504-2580","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,11]]}}}