{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T04:28:00Z","timestamp":1777868880649,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T00:00:00Z","timestamp":1502409600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T00:00:00Z","timestamp":1502409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Enzyme"],"abstract":"<jats:p>The effect of hypoparathyroidism and low blood calcium on enzyme levels in rat\nliver and kidney is shown. Four animal groups were used: parathyroidectomized (PTX), PTX\nwith CaCl(2) added in the drinking water, sham-operated controls and sham-operated with\nCaCl(2) added in the drinking water. PTX significantly lowered serum parathyroid hormone\n(PTH) and calcium. Supplementation of CaCl(2) in the drinking water increased serum Ca levels\nin PTX rats but not in the controls. Significant changes in several liver and kidney enzymes\nwere seen. Most affected were the liver NADP dependent enzymes, glucose-6-phosphate\ndehydrogenase and malic enzyme. Similar patterns but with relatively smaller changes were\nseen in the liver enzymes, lactic dehydrogenase, hexokinase, and aspartate transferase. No\nsignificant differences between the groups were seen in the levels of malic dehydrogenase,\nisocitric dehydrogenase, fructose-6-phosphate kinase and cholinesterase. In the kidney, which\nwas less affected than the liver, the only significant difference was seen in the level of malic\nenzyme. Serum total lipids in the PTX group were significantly lower. All the changes seen\nwere partially reversed by Ca supplementation in the drinking water.<\/jats:p>","DOI":"10.1159\/000469413","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T17:22:44Z","timestamp":1502472164000},"page":"94-100","source":"Crossref","is-referenced-by-count":0,"title":["Biochemical Change in the Liver and Kidney of Rats Following\nParathyroidectomy"],"prefix":"10.1159","author":[{"given":"E.","family":"Bogin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Earon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2017,8,11]]},"container-title":["Enzyme"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000469413","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T12:48:56Z","timestamp":1777553336000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000469413"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,11]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000469413","archive":["Portico"],"relation":{},"ISSN":["0013-9432","2504-2564"],"issn-type":[{"value":"0013-9432","type":"print"},{"value":"2504-2564","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,11]]}}}