{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T07:30:33Z","timestamp":1777188633074,"version":"3.51.4"},"reference-count":14,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2017,4,28]],"date-time":"2017-04-28T00:00:00Z","timestamp":1493337600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2017,4,28]],"date-time":"2017-04-28T00:00:00Z","timestamp":1493337600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Rep Ophthalmol"],"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Purpose:&lt;\/i&gt;&lt;\/b&gt; To describe the technique of limbal stem cell-sparing corneoscleroplasty for the management of advanced keratoglobus. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; A patient with bilateral advanced keratoglobus, with best-corrected visual acuity of 20\/400 in the right eye and 20\/200 in the left eye, underwent limbal stem cell-sparing corneoscleroplasty of the right eye. Initially, a 360-degree limbal incision with 200-\u03bcm depth was created, followed by a sublimbal tunnel dissection into the sclera, in order to conserve stem cells. Next, a limbus-to-limbus lamellar keratectomy at 200-\u03bcm depth was performed. Meanwhile, a donor corneoscleral button with preserved endothelium of the central 8 mm was fashioned. Prior to suturing the donor corneoscleral graft using a modified suturing technique to cover its scleral component, a full-thickness trephination of 8-mm diameter was completed in the central host cornea. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Reepithelialization occurred within the first week. No episodes of rejection, intraocular pressure spikes, or epithelial breakdown were observed postoperatively. At the 6-month follow-up, the patient had 20\/70 best-corrected vision and a smooth cornea with regular astigmatism on topography. &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; Limbal stem cell-sparing corneoscleroplasty is a single-step technique for restoring the structural integrity of the cornea in advanced keratoglobus while preserving the host limbal stem cells.<\/jats:p>","DOI":"10.1159\/000471789","type":"journal-article","created":{"date-parts":[[2017,4,28]],"date-time":"2017-04-28T21:01:33Z","timestamp":1493413293000},"page":"279-287","source":"Crossref","is-referenced-by-count":3,"title":["Limbal Stem Cell-Sparing Corneoscleroplasty with Peripheral Intralamellar Tuck: A New Surgical Technique for Keratoglobus"],"prefix":"10.1159","volume":"8","author":[{"given":"Elias","family":"Jarade","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafic","family":"Antonios","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvain","family":"el-Khoury","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2017,4,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2013.130"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0181-5512(05)81154-4"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(91)32271-1"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3182a9b1ac"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200210000-00005"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/01.ico.0000244878.38621.fc"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2007.124628"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e31823f8c85"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.4172\/2155-9899.S9-006"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6701903"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3928\/1081-597X-19890701-09"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200111000-00022"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2000.53"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/01.ico.0000157411.31566.a7"}],"container-title":["Case Reports in Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/471789","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/471789","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/471789","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T17:32:33Z","timestamp":1745429553000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000471789"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,28]]},"references-count":14,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2017,5,2]]}},"URL":"https:\/\/doi.org\/10.1159\/000471789","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.4929821","asserted-by":"subject"}]},"ISSN":["1663-2699"],"issn-type":[{"value":"1663-2699","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,28]]}}}