{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T15:06:02Z","timestamp":1784214362468,"version":"3.55.0"},"reference-count":28,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatology"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; The therapeutic decision to close patent ductus arteriosus in preterm infants entails great uncertainty. Near-infrared spectroscopy is a noninvasive bedside technique used to monitor mixed regional oxygen saturation. We hypothesized that near-infrared spectroscopy could identify preterm infants at risk of mesenteric hypoperfusion associated with hemodynamically significant ductus arteriosus. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; This is a prospective observational study including consecutively admitted preterm infants with a gestational age &lt;32 weeks. Mesenteric regional oxygenation was blindly monitored using an INVOS 5100 device. The presence of a hemodynamically significant patent ductus arteriosus was routinely confirmed by echocardiography\/Doppler. Statistical analysis including Bland-Altman plots was performed to assess near-infrared spectroscopy intraobserver repeatability. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; A total of 72 preterm infants were enrolled. The daily mean regional oxygen saturation for preterm infants was determined both in mesenteric and cerebral regions and plotted against time. We identified a differential temporary baseline. Hemodynamic significant ductus arteriosus was associated with lower blood pressures and lower regional splanchnic oxygenation. There was a significant relationship between reversal diastolic flow in the descending aorta and the regional oxygen saturation, which remained significant after controlling for ductal size and nil per os. &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; The simultaneous monitoring of splanchnic near-infrared spectroscopy and echocardiography could identify low mesenteric perfusion in the presence of hemodynamic ductus arteriosus.<\/jats:p>","DOI":"10.1159\/000475933","type":"journal-article","created":{"date-parts":[[2017,7,13]],"date-time":"2017-07-13T21:01:29Z","timestamp":1499979689000},"page":"238-245","source":"Crossref","is-referenced-by-count":36,"title":["Abdominal Near-Infrared Spectroscopy Detects Low Mesenteric Perfusion Early in Preterm Infants with Hemodynamic Significant Ductus Arteriosus"],"prefix":"10.1159","volume":"112","author":[{"given":"Ana","family":"Ledo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Aguar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"N\u00fa\u00f1ez-Ramiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pilar","family":"Sa\u00e9nz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0061-4742","authenticated-orcid":false,"given":"M\u00e1ximo","family":"Vento","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2017,7,14]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-3506"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-1528"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1080\/08035250119151"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2006.12.048"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1754.1994.tb00689.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jp.7211294"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2009.02575.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s001340100994"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2011.11.054"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s004310051046"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0000000000000211"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2012.108"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(78)80282-0"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-836555"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2010.511335"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1203\/PDR.0b013e31815b4830"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(95)70172-9"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2010.71"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3233\/NPM-15814090"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2011.03263.x"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.2450\/2015.0212-14"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1038\/pr.2014.52"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3233\/NPM-1365112"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1159\/000445283"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2010.200"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-199106010-00010"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1203\/PDR.0b013e31822e178e"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-2108"}],"container-title":["Neonatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/475933","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/475933","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:24:31Z","timestamp":1745425471000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000475933"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":28,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2017,10,6]]}},"URL":"https:\/\/doi.org\/10.1159\/000475933","archive":["Portico"],"relation":{},"ISSN":["1661-7800","1661-7819"],"issn-type":[{"value":"1661-7800","type":"print"},{"value":"1661-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}