{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T06:09:21Z","timestamp":1788847761963,"version":"build-2803163510"},"reference-count":32,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cardiology"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Objectives:&lt;\/i&gt;&lt;\/b&gt; Detection of atrial fibrillation (AF) in post-cryptogenic stroke (CS) or transient ischemic attack (TIA) patients carries important therapeutic implications. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; To risk stratify CS\/TIA patients for later development of AF, we conducted a retrospective cohort study using data from 1995 to 2015 in the Stanford Translational Research Integrated Database Environment (STRIDE). &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Of the 9,589 adult patients (age \u226540 years) with CS\/TIA included, 482 (5%) patients developed AF post CS\/TIA. Of those patients, 28.4, 26.3, and 45.3% were diagnosed with AF 1-12 months, 1-3 years, and &gt;3 years after the index CS\/TIA, respectively. Age (\u226575 years), obesity, congestive heart failure, hypertension, coronary artery disease, peripheral vascular disease, and valve disease are significant risk factors, with the following respective odds ratios (95% CI): 1.73 (1.39-2.16), 1.53 (1.05-2.18), 3.34 (2.61-4.28), 2.01 (1.53-2.68), 1.72 (1.35-2.19), 1.37 (1.02-1.84), and 2.05 (1.55-2.69). A risk-scoring system, i.e., the HAVOC score, was constructed using these 7 clinical variables that successfully stratify patients into 3 risk groups, with good model discrimination (area under the curve = 0.77). &lt;b&gt;&lt;i&gt;Conclusions:&lt;\/i&gt;&lt;\/b&gt; Findings from this study support the strategy of looking longer and harder for AF in post-CS\/TIA patients. The HAVOC score identifies different levels of AF risk and may be used to select patients for extended rhythm monitoring.<\/jats:p>","DOI":"10.1159\/000476030","type":"journal-article","created":{"date-parts":[[2017,6,27]],"date-time":"2017-06-27T21:01:22Z","timestamp":1498597282000},"page":"133-140","source":"Crossref","is-referenced-by-count":105,"title":["A Clinical Score for Predicting Atrial Fibrillation in Patients with Cryptogenic Stroke or Transient Ischemic Attack"],"prefix":"10.1159","volume":"138","author":[{"given":"Calvin","family":"Kwong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albee Y.","family":"Ling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael H.","family":"Crawford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan X.","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigam H.","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2017,6,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.602615"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.25.2.333"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.22.8.983"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000024"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.589218"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1311376"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1313600"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136\/amiajnl-2014-002902"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2013.47"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1186\/1546-0096-11-45"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136\/amiajnl-2011-000744"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2009.05.002"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.29.8.1602"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/ene.12017"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.7.2455"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-0331"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1742"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111\/j.0006-341X.2000.00345.x"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-1584"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0b013e318284056a"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2010.11.011"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.109.552679"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.114.007763"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2014.08.016"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2013.01.335"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.029801"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)70027-X"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60443-8"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.10725"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2013-305303"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2015.04.002"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.63.6266"}],"container-title":["Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/476030","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/476030","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:25:35Z","timestamp":1745425535000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000476030"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":32,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2017,11,2]]},"published-print":{"date-parts":[[2017,11,7]]}},"URL":"https:\/\/doi.org\/10.1159\/000476030","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.5146912","asserted-by":"subject"}]},"ISSN":["0008-6312","1421-9751"],"issn-type":[{"value":"0008-6312","type":"print"},{"value":"1421-9751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}