{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:07:57Z","timestamp":1787836077395,"version":"build-2784847793"},"reference-count":0,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2017,7,13]],"date-time":"2017-07-13T00:00:00Z","timestamp":1499904000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2017,7,13]],"date-time":"2017-07-13T00:00:00Z","timestamp":1499904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"published-print":{"date-parts":[[2018]]},"abstract":"<b><i>Background:<\/i><\/b> Prenatal detection of excessive growth remains inaccurate. Most strategies rely on a single cross-sectional evaluation of fetal size during the third trimester. <b><i>Objectives:<\/i><\/b> To compare second- to third-trimester longitudinal growth assessment with cross-sectional evaluation at the third trimester in the prediction of largeness for gestational age (LGA) and macrosomia. <b><i>Methods:<\/i><\/b> A cohort of 2,696 unselected singleton pregnancies scanned at 21 \u00b1 2 and 32 \u00b1 2 weeks was created. Abdominal circumference (AC) measurements were transformed to <i>z<\/i> values according to the INTERGROWTH-21st standards. Longitudinal growth assessment was performed by calculation of <i>z<\/i> velocity and conditional growth. Both methods were compared to cross-sectional assessment at 32 \u00b1 2 weeks. Predictive performance for LGA and macrosomia was determined by receiver operating characteristic curve analysis. <b><i>Result:<\/i><\/b> A total of 188 (7%) newborns qualified for LGA and 182 (6.8%) for macrosomia. The areas under the curve (AUCs) for 32-week AC <i>z<\/i> score, AC <i>z<\/i> velocity, and conditional AC were 0.78, 0.61, and 0.55, respectively, for the prediction of LGA, and 0.75, 0.61, and 0.55, respectively, for the prediction of macrosomia. Both AUCs of AC <i>z<\/i> velocity and conditional AC were significantly lower (<i>p<\/i> < 0.001) than the AUC of cross-sectional AC <i>z<\/i> scores. <b><i>Conclusions:<\/i><\/b> In the general population, second- to third-trimester longitudinal assessment of fetal growth is inferior to third-trimester cross-sectional evaluation of size in the prediction of LGA and macrosomia.<\/jats:p>","DOI":"10.1159\/000477460","type":"journal-article","created":{"date-parts":[[2017,7,18]],"date-time":"2017-07-18T21:01:19Z","timestamp":1500411679000},"page":"284-290","source":"Crossref","is-referenced-by-count":10,"title":["Second- to Third-Trimester Longitudinal Growth Assessment for the Prediction of Largeness for Gestational Age and Macrosomia in an Unselected Population"],"prefix":"10.1159","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9504-4596","authenticated-orcid":false,"given":"Javier","family":"Caradeux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisenda","family":"Eixarch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edurne","family":"Mazarico","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tri Rahmat","family":"Basuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduard","family":"Gratac\u00f3s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesc","family":"Figueras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2017,7,13]]},"container-title":["Fetal Diagnosis and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/477460","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/477460","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:30:09Z","timestamp":1745425809000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000477460"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,13]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2018,5,29]]},"published-print":{"date-parts":[[2018,6,5]]}},"URL":"https:\/\/doi.org\/10.1159\/000477460","archive":["Portico"],"relation":{"is-supplemented-by":[{"id-type":"doi","id":"10.6084\/m9.figshare.5216545","asserted-by":"subject"}]},"ISSN":["1015-3837","1421-9964"],"issn-type":[{"value":"1015-3837","type":"print"},{"value":"1421-9964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7,13]]}}}