{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T13:43:40Z","timestamp":1790430220131,"version":"4.1.0"},"reference-count":23,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Stereotact Funct Neurosurg"],"published-print":{"date-parts":[[2017]]},"abstract":"<b><i>Background:<\/i><\/b> Treatment options for patients with drug-resistant essential tremor (ET) are limited. Magnetic resonance-guided focused ultrasound surgery (MRgFUS) is an emerging technique to treat refractory ET. <b><i>Objectives:<\/i><\/b> To present MRgFUS as an alternative to radiofrequency (RF) thalamotomy or deep brain stimulation (DBS) for ET treatment. <b><i>Methods:<\/i><\/b> We retrospectively analyzed 59 patients who underwent unilateral surgery for drug-resistant ET. Treatments included RF thalamotomy (<i>n<\/i> = 17), DBS (<i>n<\/i> = 19), and MRgFUS (<i>n<\/i> = 23). The outcomes measured were tremor severity and treatment-related complications. <b><i>Results:<\/i><\/b> At 1 month postoperatively, 100% of RF thalamotomy patients, 89.5% of DBS patients, and 91.3% of MRgFUS patients exhibited absent\/mild tremor (successful treatment); other patients exhibited partial relief. At 12 months postoperatively, treatment success for each procedure was observed in 70.6, 84.2, and 78.3% of patients, respectively. At 1 month postoperatively, treatment-related complications had occurred in 58.8, 5.3, and 13.0% of patients, respectively. At 12 months postoperatively, side effects persisted in 11.8, 21.1, and 4.4% of patients, respectively. No statistical differences in treatment success were observed between treatments or over time. Complication rates differed between treatment modalities (<i>p<\/i> < 0.01) and were lowest in the MRgFUS group. <b><i>Conclusions:<\/i><\/b> Patients with drug-resistant ET received equivalent results from RF thalamotomy, DBS, and MRgFUS. DBS and MRgFUS resulted in fewer treatment-related complications.<\/jats:p>","DOI":"10.1159\/000478866","type":"journal-article","created":{"date-parts":[[2017,8,15]],"date-time":"2017-08-15T21:01:32Z","timestamp":1502830892000},"page":"279-286","source":"Crossref","is-referenced-by-count":63,"title":["Comparative Evaluation of Magnetic Resonance-Guided Focused Ultrasound Surgery for Essential Tremor"],"prefix":"10.1159","volume":"95","author":[{"given":"Minsoo","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na Young","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang Kyu","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won Seok","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Ho","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2717-0101","authenticated-orcid":false,"given":"Jin Woo","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2017,8,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23284"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10376"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(05)70226-X"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/123.4.665"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1986.65.3.0296"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200002173420703"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/mds.23195"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/47\/8\/301"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1121\/1.1529663"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000360379.95800.2F"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2014-307642"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1403.2012.00503.x"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e318236f0fd"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1159\/000342491"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1996.84.2.0203"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26625"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/BF01412303"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1300962"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70048-6"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1600159"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awm266"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1097\/WNF.0b013E31807A32C6"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1002\/mds.21412"}],"container-title":["Stereotactic and Functional Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/478866","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/478866","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:40:12Z","timestamp":1745426412000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000478866"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":23,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2017,9,11]]}},"URL":"https:\/\/doi.org\/10.1159\/000478866","archive":["Portico"],"relation":{},"ISSN":["1011-6125","1423-0372"],"issn-type":[{"value":"1011-6125","type":"print"},{"value":"1423-0372","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}