{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T03:19:49Z","timestamp":1782789589475,"version":"3.54.5"},"reference-count":24,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatology"],"published-print":{"date-parts":[[2017]]},"abstract":"<jats:p>&lt;b&gt;&lt;i&gt;Background:&lt;\/i&gt;&lt;\/b&gt; Congenital diaphragmatic hernia (CDH) is an abnormal development of the diaphragm leading to high neonatal mortality and morbidity. Beyond the neonatal period, prospective data on overall long-term outcome in CDH survivors is scarce. In particular, for those treated with fetoscopic endoluminal tracheal occlusion (FETO), a promising new technique to increase survival chances for severe cases, the outcomes are even less documented. &lt;b&gt;&lt;i&gt;Aim:&lt;\/i&gt;&lt;\/b&gt; To prospectively document the clinical outcome of CDH at 1 year including FETO-treated infants in relation to ante- and postnatal variables. &lt;b&gt;&lt;i&gt;Methods:&lt;\/i&gt;&lt;\/b&gt; A single-centre prospective clinical follow-up at 1 year of age included a standardised respiratory questionnaire. &lt;b&gt;&lt;i&gt;Results:&lt;\/i&gt;&lt;\/b&gt; Thirty-four CDH survivors were included, 10 of which were FETO-treated infants. At 1 year, the median weight &lt;i&gt;z&lt;\/i&gt; score was -1.50 (interquartile range [IQR]: -2.45 to -0.88) and 10\/34 were \u201cfailure to thrive\u201d (FTT) cases. Gastro-intestinal (GI) problems at 1 year were mainly related to gastro-oesophageal reflux (16\/34) with a high need for tube feeding in the first year (9\/34). Tachypnoea was present in 10\/29 (34%) and 8\/34 (24%) were on chronic inhaled medication. The median total respiratory symptom score was 20 (IQR: 13-32) and correlated with the number of neonatal ventilation days (&lt;i&gt;p&lt;\/i&gt; = 0.048). Hospital re-admission occurred in 19\/34 infants (56%), and was for respiratory problems in almost half of them (8\/19). &lt;b&gt;&lt;i&gt;Conclusion:&lt;\/i&gt;&lt;\/b&gt; In this CDH cohort, morbidity at 1 year was determined more by GI problems and FTT than respiratory morbidity. The respiratory questionnaire may, however, have underestimated the respiratory morbidity since respondents had a 1-in-4 chance to have persistent tachypnoea and be on chronic inhalation therapy.<\/jats:p>","DOI":"10.1159\/000479145","type":"journal-article","created":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T21:01:21Z","timestamp":1504299681000},"page":"365-371","source":"Crossref","is-referenced-by-count":23,"title":["Clinical Outcome for Congenital Diaphragmatic Hernia at the Age of 1 Year in the Era of Fetal Intervention"],"prefix":"10.1159","volume":"112","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8621-7718","authenticated-orcid":false,"given":"Eva","family":"Van Ginderdeuren","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9921-5105","authenticated-orcid":false,"given":"Karel","family":"Allegaert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert","family":"Decaluwe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4920-945X","authenticated-orcid":false,"given":"Jan","family":"Deprest","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Debeer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marijke","family":"Proesmans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2017,9,2]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2012.10.007"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2013.11.005"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/uog.4052"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002\/uog.6450"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4642"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/uog.12445"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2014.09.006"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2007.01.009"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000000454"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2013.168"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2013.08.014"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3109\/03014460903049074"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)62226-X"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1136\/adc.87.5.376"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1159\/000444210"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2014.10.003"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2015.02.026"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-008-2257-y"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-200X.2007.02527.x"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i28.8508"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-008-9738-y"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2011.03.085"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezt001"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2014.01.016"}],"container-title":["Neonatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/479145","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/479145","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T16:42:45Z","timestamp":1745426565000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000479145"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017]]},"references-count":24,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2017,11,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000479145","archive":["Portico"],"relation":{},"ISSN":["1661-7800","1661-7819"],"issn-type":[{"value":"1661-7800","type":"print"},{"value":"1661-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017]]}}}